496 Pages 301 B/W Illustrations
    by CRC Press

    Mass Spectrometry Basics provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. The authors describe processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. The text provides practical approaches to interpreting mass spectral data and step-by-step guides for identifying chemically relevant compounds. Additionally, the authors have included an extensive reference section and a quick guide to each chapter that offers immediate access to key information.

    This unique reference makes some of the esoteric aspects of this important area of analysis more readily comprehensible to those who deal with analytical instruments but who have not been trained in mass spectrometry. It also serves as a refresher for practicing mass spectroscopists by clarifying principles to afford a better appreciation and application of this technology.

    Chemical Ionisation (CI)
    Laser Desorption Ionisation (LDI)
    Electron Ionisation (EI)
    Fast Atom Bombardment (FAB) and Liquid Phase Secondary Ion Mass Spectrometry (LSIMS) Ionisation
    Field Ionisation (FI) and Field Desorption (FD)
    Coronas, Plasmas and Arcs
    Thermal Ionisation (TI; Surface Emission of Ions)
    Electrospray Ionisation (ES)
    Atmospheric Pressure Ionisation (API)
    Z-Spray Combined Inlet/Ion Source
    Thermospray and Plasmaspray Interface
    Particle-Beam Interface
    Dynamic Fast Atom Bombardment and Liquid (phase) Secondary Ion Mass Spectrometry (FAB/LSIMS) Interface
    Plasma Torches
    Sample Inlets for Plasma Torches. Part A: Gases
    Sample Inlets for Plasma Torches. Part B: Liquid Inlets
    Sample Inlets for Plasma Torches. Part C: Solid Inlets
    Lasers and Other Light Sources
    Nebulisers
    Hybrid Orthogonal Time-of-Flight (oa-TOF) Instruments
    Hybrid Magnetic Sector Time-of-Flight (TOF) Instruments
    Hybrid Hexapole Time-of-Flight (TOF) Instruments
    Hybrid Quadrupole Time-of-Flight (TOF) Instruments
    Ion Optics of Magnetic/Electric Sector Mass Spectrometers
    Quadrupole Ion Optics
    Time-of-Flight (TOF) Ion Optics
    Orthogonal Time of Flight (oa-TOF) Ion Optics
    Point Ion Collectors (Detectors)
    Array Collectors (Detectors)
    Comparison of Multipoint Collectors (Detectors) of Ions
    Time-to-Digital Converters
    Origin and Uses of Metastable Ions
    Linked Scanning and Metastable Ions in Quadrupole Mass Spectrometry
    Linked Scanning and Metastable Ions in Magnetic Sector Mass Spectrometry
    Gas Chromatography (GC) and Liquid Chromatography (LC)
    Gas Chromatography / Mass Spectrometry (GC/MS)
    Liquid Chromatography / Mass Spectrometry (LC/MS)
    High Resolution Accurate Mass Measurement: Element Compositions
    Choice of Mass Spectrometer
    Analysis of Peptides and Proteins by Mass Spectrometry
    EPA Protocols
    Computers and Transputers in Mass Spectrometers, Part A
    Computers and Transputers in Mass Spectrometers, Part B
    Computers and Transputers in Mass Spectrometers, Part C
    An Introduction to Biotechnology
    Isotopes and Mass Spectrometry
    Use of Isotope Ratios
    Variations in Isotope Ratios
    Transmission of Ions through Inhomogeneous RF Fields
    Appendices

    Biography

    Herbert, Christopher G.; Johnstone, Robert A.W.

    "This book is intended … as a brief primer on the many flavors and applications of MS technology. As such, the novice will walk away with a taste of MS while the seasoned pioneer will see this book as a quick reference. … [T]he book sets the reader up to read … more complex books down the road. And each chapter is spiced with figures, tables, and schematics that help the reader understand how this technology comes together."
    - Today's Chemist at Work



    "…can be used by all categories of readership…The book is developmental in nature - beginning with basics of the process and proceeding stepwise to more detailed analyses of each aspect of the method…Highly recommended"
    L. Andersson, Big Bend Community College, in CHOICE Magazine.


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