1st Edition
Mass Spectrometry Basics
Mass Spectrometry Basics provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. The authors describe processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. The text provides practical approaches to interpreting mass spectral data and step-by-step guides for identifying chemically relevant compounds. Additionally, the authors have included an extensive reference section and a quick guide to each chapter that offers immediate access to key information.
This unique reference makes some of the esoteric aspects of this important area of analysis more readily comprehensible to those who deal with analytical instruments but who have not been trained in mass spectrometry. It also serves as a refresher for practicing mass spectroscopists by clarifying principles to afford a better appreciation and application of this technology.
Laser Desorption Ionisation (LDI)
Electron Ionisation (EI)
Fast Atom Bombardment (FAB) and Liquid Phase Secondary Ion Mass Spectrometry (LSIMS) Ionisation
Field Ionisation (FI) and Field Desorption (FD)
Coronas, Plasmas and Arcs
Thermal Ionisation (TI; Surface Emission of Ions)
Electrospray Ionisation (ES)
Atmospheric Pressure Ionisation (API)
Z-Spray Combined Inlet/Ion Source
Thermospray and Plasmaspray Interface
Particle-Beam Interface
Dynamic Fast Atom Bombardment and Liquid (phase) Secondary Ion Mass Spectrometry (FAB/LSIMS) Interface
Plasma Torches
Sample Inlets for Plasma Torches. Part A: Gases
Sample Inlets for Plasma Torches. Part B: Liquid Inlets
Sample Inlets for Plasma Torches. Part C: Solid Inlets
Lasers and Other Light Sources
Nebulisers
Hybrid Orthogonal Time-of-Flight (oa-TOF) Instruments
Hybrid Magnetic Sector Time-of-Flight (TOF) Instruments
Hybrid Hexapole Time-of-Flight (TOF) Instruments
Hybrid Quadrupole Time-of-Flight (TOF) Instruments
Ion Optics of Magnetic/Electric Sector Mass Spectrometers
Quadrupole Ion Optics
Time-of-Flight (TOF) Ion Optics
Orthogonal Time of Flight (oa-TOF) Ion Optics
Point Ion Collectors (Detectors)
Array Collectors (Detectors)
Comparison of Multipoint Collectors (Detectors) of Ions
Time-to-Digital Converters
Origin and Uses of Metastable Ions
Linked Scanning and Metastable Ions in Quadrupole Mass Spectrometry
Linked Scanning and Metastable Ions in Magnetic Sector Mass Spectrometry
Gas Chromatography (GC) and Liquid Chromatography (LC)
Gas Chromatography / Mass Spectrometry (GC/MS)
Liquid Chromatography / Mass Spectrometry (LC/MS)
High Resolution Accurate Mass Measurement: Element Compositions
Choice of Mass Spectrometer
Analysis of Peptides and Proteins by Mass Spectrometry
EPA Protocols
Computers and Transputers in Mass Spectrometers, Part A
Computers and Transputers in Mass Spectrometers, Part B
Computers and Transputers in Mass Spectrometers, Part C
An Introduction to Biotechnology
Isotopes and Mass Spectrometry
Use of Isotope Ratios
Variations in Isotope Ratios
Transmission of Ions through Inhomogeneous RF Fields
Appendices
Biography
Herbert, Christopher G.; Johnstone, Robert A.W.
"This book is intended … as a brief primer on the many flavors and applications of MS technology. As such, the novice will walk away with a taste of MS while the seasoned pioneer will see this book as a quick reference. … [T]he book sets the reader up to read … more complex books down the road. And each chapter is spiced with figures, tables, and schematics that help the reader understand how this technology comes together."
- Today's Chemist at Work
"…can be used by all categories of readership…The book is developmental in nature - beginning with basics of the process and proceeding stepwise to more detailed analyses of each aspect of the method…Highly recommended"
L. Andersson, Big Bend Community College, in CHOICE Magazine.
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