Lung Injury: Mechanisms, Pathophysiology, and Therapy

1st Edition

Robert H. Notter, Jacob Finkelstein, Bruce Holm

CRC Press
Published April 20, 2005
Reference - 888 Pages - 97 B/W Illustrations
ISBN 9780824757939 - CAT# DK1263
Series: Lung Biology in Health and Disease

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Summary

Progressing from general scientific principles and concepts to in-depth topical discussions of current research and treatment methods, this comprehensive reference defines the cellular and molecular mechanisms contributing to inflammatory lung injury and repair. Extensive coverage is provided on key mediators and pathways important in acute and chronic pulmonary inflammation and lung injury, as well as the mechanistic pathophysiology of related diseases ranging from clinical acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) to idiopathic pulmonary fibrosis (IPF) and other subacute and chronic conditions. Additional chapters also address vascular dysfunction, surfactant dysfunction, reactive oxygen/nitrogen species, and cell and animal models of acute and chronic lung injury.

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