1st Edition
Liver Diseases (2 Vols.) Biochemical Mechanisms and New Therapeutic Insights
This book presents state-of-art information summarizing the current understanding of a range of liver diseases, and reviews some key diagnostic and therapeutic advances. The book is a collection of selected clinical and scientific topics divided into two volumes, each divided into two sections. The first volume treats the cellular, biochemical and immunological mechanisms underlying liver diseases; the second focuses on clinical liver disease pathophysiology and related diagnostics and therapeutic insights. It is hoped that the target readers - hepatologists, clinicians, researchers and cademicians - will be exposed to new ideas, and subjects beyond their own scientific disciplines. In addition, students and all those who wish to enlarge their knowledge of advances in the field of liver diseases will find this book a good source of information.
VOLUME 1: LIVER DISEASES: PATHWAYS, MEDIATORS AND REGULATION
Section I: Liver Diseases: Mediators and Regulation: Ubiquitin - Proteasome Pathway in the Pathogenesis of Liver Disease
Bardag-Gorce
Collagen Gene Regulation in the Hepatic Stellate Cell
Rippe
CYP2F1-Biochemical and Toxicological Aspects and Role in Alcohol-induced Liver Injury
Cederbaum
Alcohol and Methyl Transfer: Implications for Alcohol-Related Hepatocarcinogenesis
Menthionine Adenosyltransferase and S-adenosylmethionine in Liver Health and Disease
Acetone Metabolism in the Liver
Oxidative Stress and Liver Fibrosis: From Liver Injury to Modulation of Cell Signalling and Response
Role of Nitric Oxide in Liver Disorders
Renin-Angiotensin System in Liver Fibrosis
Section II: Immunological Basis of Liver Injury: Cell and Molecular Mechanisms in the Development of Chronic Liver Inflammation
Role of Activated Macrophages in Liver Disease
Investigations into Basis for Immune Recognition of Cellular Targets in Primary Biliary Cirrhosis
Cross Talk of Hepatocytes and Nonparenchymal Liver Cells in Physiology and Pathology: Monoxides and Eicosanoids
Activity of Cytokines in Chronic HCV Infection and Influence of Antiviral Drugs
Role of Chemokines in Liver Pathophysiology
VOLUME 2: CLINICAL LIVER DISEASES: PATHOPHYSIOLOGY, DIAGNOSTIC AND THERAPEUTIC INSIGHTS:
Section III: Clinical Liver Disease Pathophysiology: Nonalcoholic Fatty Liver Diseases: Clinical and Pathophysiological Features
Genetic Basis of Hepatocellular Cancer
Haemochromatosis: Recent Advances
Pathophysiology of Cirrhotic Ascites: Recent Advances
Cryptogenic Hepatitis
HIV-1 and the Liver
Cell Death by Necrosis: Mechanisms and Interception in the Liver
Fulminant Hepatic Failure: Etiology, Pathogenesis, and Treatment
Section IV: Therapeutic and Diagnostic Insights: Advances in Biology and Therapy of Hepatitis B Virus Infection
Hepatitis C Virus: Molecular Virology and Therapeutic Targets
Drug Targeting to Hepatic Stellate Cells: A New Strategy to Treat Liver Fibrosis
Developing Therapeutic Strategies for Hepatic Fibrosis
Liver Disease, Oxidative Stress and Ursodeoxycholic Acid
Plasma TGF-b as a Diagnostic and Prognostic Marker
Hepatocytes as the Gold Standard for Predicting in-vivo Hepatotoxicity of Xenobiotics Using Accelerated Cytotoxicity Mechanism Screening Techniques
Biography
Ali, Shakir ; Friedman, Scott L.
