Although the role of liposomes in drug targeting has been discussed extensively in several reviews and books, there has been no comprehensive coverage of related methodology. This book constitutes the first attempt to put together all aspects of lipsome technology as applied to medical sciences. Volume I deals directly with methods for the preparation of liposomes and auxiliary techniques.
Table of Contents
1. Physicochemical Properties of Phospholipids and Lipid-Water Systems 2. A Simple Procedure for Preparing Liposomes Capable of High Encapsulation Efficiency Under Mild Conditions 3. Preparation of Solvent Vaporization Liposomes 4. French Pressure Cell Liposomes: Preparation, Properties, and Potential 5. The Use of French Pressed Vesicles for Efficient Incorporation of Bioactive Macromolecules and as Drug Carriers In Vitro and In Vivo 6. Formation of Unilamellar Liopsomes by pH Adjustment 7. The Preparation of Variably Sized Homogenous Liposomes for Laboratory, Clinical and Industrial Use by Controlled Detergent Dialysis 8. Removal of Detergent and Solvent Traces from Liposomes 9. Polymerized Liposomes and Vesicles 10. The Preparation of Sterile Drug-Containing Liposomes 11. The Preparation of Sterile Drug-Containing Liposomes 12. Lipid Peroxidation in Liposomes 13. Size Distribution Analysis of Liposomes by Electron Microscopy 14. Hydrophobic Affinity Partition of Liposomes in Aqueous Two-Phase Systems 15. Applications of a Technique for Rapid Separation of Liposomes from Cells in Culture 16. Freezing and Thawing of Liposome Suspensions 17. Freezing of Liposomes 18. Stability Testing of Liposomes During Storage 19. Preparation of Liposomes on the Industrial Scale: Problems and Perspectives