Liposome Technology, Second Edition, is an updated, expanded new edition of a classic volume in the field. It covers all aspects of liposome technology, including liposome preparation and analysis, drug entrapment, and techniques used for in vivo and in vitro evaluation of liposomes. Leading authorities have contributed 70 chapters to create what is destined to be the standard liposome technology book for the 1990s. Many of the chapters describe methodologies practiced in authors' laboratories and provide specific examples of how these methodologies are applied in specific circumstances.
Liposome Technology, Second Edition will be an essential reference volume for academic and industrial researchers in pharmacology, pharmacy, medicine, biochemistry, and immunology.
What's new in the 2nd Edition?
The 2nd Edition covers significant developments in liposome technology that have occurred since the publication of the 1st Edition in 1982. These developments include the following:
New preparative procedures
Special approaches to accommodate the incorporation of certain drugs
New targeting techniques
Large scale production of liposomes, patents, and clinical trials
Table of Contents
VOLUME II: ENTRAPMENT OF DRUGS AND OTHER MATERIALS
Binding of Charged Molecules to Lipid Bilayers (A.G. Lee and S. Schreier). pH Gradient-Mediated Drug Entrapment in Liposomes (Lawrence D. Mayer, Thomas D. Madden, Marcel B. Bally, and Pieter R. Cullis). Incorporation of Immunomodulators in Liposomes for Systemic Activation of Macrophages and Therapy of Cancer Metastasis (Isaiah J. Fidler). Liposomal Paramagnetic Magnetic Resonance Contrast Agents (Colin Tilcock). A Comparison of Methods for the Preparation of Lipopolysaccharide Containing Liposomes (Jan Dijkstra). Liposome-Encapsulated Interferon Alpha: A Model for Receptor-Independent Delivery of Growth-Inhibitory Peptides (Jerald J. Killion and Isaiah J. Fidler). Incorporation of Membrane Proteins into Liposomes and Their Detection by Antibodies (Hakan Eriksson). Incorporation of Genetic Material into Liposomes and Transfer to Cells (Paul F. Lurquin). Liposomes as Vehicles for the Presentation of Tumor-Associated Antigens to the Immune System (J.J. Bergers, G. Storm, and W. Den Otter). Liposomes as Adjuvants for Peptides: Preparation and Use of Immunogenic Peptide-Phospholipid Complexes (Raphael J. Mannino, Susan Gould Fogerite, and Gail Goodman-Snitkoff). Modulation of the Immune Response Against Liposomes Containing Liposoluble Immunogenic Materials (Guy J. W.J. Zigterman, Margriet Jansze, and Harm Snippe). Liposomes in the Cosmetics Industry (R.M. Handjani-Vila, A. Ribier, and G. Vanlerberghe). Controlled Delivery of Functional Food Ingredients: Opportunities for Liposomes in the Food Industry (Christopher J. Kirby). The Interaction of Detergents with Liposomal Membranes (Jurgen Lasch and Rolf Schubert). Effect of Surfactants on the Release of Liposomal (Felix M. Goni, Maria-Angeles Urbaneja, and Alicia Alonso). Role of Liposome Composition on Drug Stability (Satish K. Pejaver). A New Membraneless Dynamic-Dialysis Cell for Rapid Measurements of Dilution-Induced Drug Release from Liposomes (Shulamit Levin and Tali Bar-Shua). Design of Liposome Clinical Trials (Cary A. Presant, Roger Crossley, Gunter Ksionski, and Richard Proffitt). Liposome-Related U.S. Patents (Carl F. Grove and Marilyn Jensen).