Kidney: Toxicological Assessment

Sang Geon Kim

September 11, 2013 by CRC Press
Reference - 234 Pages - 13 Color & 30 B/W Illustrations
ISBN 9781466588110 - CAT# K20368


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  • Discusses the increasing quantities of toxicants in the environment and how they affect human organs
  • Covers toxicity caused in kidney as a major health issue
  • Studies this issue with the aid of modern medical techniques such as microimaging, stem cell biology, proteomics, small RNAs etc.


Bridging the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments, this book describes major areas of progress in the laboratory and clinic. In the first section, aspects of cellular organelles are discussed. The second section covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. In the third section, the recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally, the book discusses clinical implications of acute and chronic renal toxicity.