Ion and Molecule Transport in Lysosomes

1st Edition

Bruno Gasnier, Michael X. Zhu

CRC Press
June 5, 2020 Forthcoming
Reference - 264 Pages - 24 Color & 8 B/W Illustrations
ISBN 9781138560390 - CAT# K43421
Series: Methods in Signal Transduction Series

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Summary

Lysosomes are key subcellular organelles that regulate the cell function. Many of the essential activities of the cell are dependent on lysosomes. Dysfunction is linked to multiple diseases - storage disorders, neurodegeneration, immunological diseases and cancer. This book discusses concepts and methods used to study lysosome ion and small molecule transport. The contents will not only attract accomplished investigators in need of a broad review and synthesis of this important subject but will also appeal to young investigators and trainees needing to acquire comprehensive knowledge and technical skills working with lysosomal ion channels and small molecule transporters.

Key selling features:

  • Summarizes the endocellular role that lysosomes play with respect to cellular waste disposal
  • Reviews essential cellular functions of lysosomes
  • Explores how lysosome dysfunction is the cause of many metabolic disorders
  • Examines how lysomes are involved in storage diseases
  • Describes various technologies and methods used in lysosome research
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