1st Edition
Introduction to Integrative Engineering A Computational Approach to Biomedical Problems
This textbook is designed for an introductory course at undergraduate and graduate levels for bioengineering students. It provides a systematic way of examining bioengineering problems in a multidisciplinary computational approach. The book introduces basic concepts of multidiscipline-based computational modeling methods, provides detailed step-by-step techniques to build a model with consideration of underlying multiphysics, and discusses many important aspects of a modeling approach including results interpretation, validation, and assessment.
Part 1: Readying the Integrative Mindset
Chapter One: From Compartmentalized Disciplines to Trans-Discipline
Part 2: Cracking Open the Blackbox of Computational Modeling
Chapter Two: Engineering Problems and Partial Differential Equations
Chapter Three: Where Do Differential Equations Come From?
Chapter Four: Approximate Solutions to Differential Equations
Chapter Five: Discretization of Physical Domains
Chapter Six: Solving Differential Equations Computationally
Chapter Seven: Scalar Field Problems in Higher Dimensions
Chapter Eight: Vector Field Problems in Higher Dimensions
Chapter Nine: Axisymmetric Scalar and Vector Field Problems
Chapter Ten: Isoparametric Elements
Chapter Eleven: Gauss Quadrature and Numerical Integration
Chapter Twelve: Dealing with Generalized PDEs
Chapter Thirteen: Errors in FEM Results
Part 3: Developing Hands-On Modeling Skills
Chapter Fourteen: A Quick Tour of the COMSOL Modeling Environment
Chapter Fifteen: A Glimpse of the ABAQUS and ANSYS User Interfaces
Chapter Sixteen: Dealing with Problems of Biomedical and Regulatory Interest
Part 4: Useful Knowledge
Appendix A: Mechanics of Materials
Appendix B: Useful Mathematic Knowledge
Biography
Guigen Zhang, Ph.D., is Professor of Bioengineering and Professor of Electri- cal and Computer Engineering at Clemson University. He is also the Executive Director of the Institute for Biological Interfaces of Engineering, a research and education/training institute designated by the South Carolina Commission on Higher Education. Professor Zhang is a fellow of the American Institute for Medical and Biological Engineering (AIMBE). He has published extensively in the areas of biosensors, biomechanics, biomaterials and computational modeling. Over the years, his research has been funded by diverse funding sources ranging from federal agencies such as National Institutes for Health and National Science Foundation, to private foundations like the Bill and Melinda Gates Foundation, to venture groups and state-level startup funds, as well as industries in the health-care, semiconductors, and data-storage sectors. Professor Zhang holds numerous patents in nanotechnology-enhanced structures and biosensors. Aside from his services on the editorial boards of numerous scientific journals, Pro- fessor Zhang is also active in serving leadership roles in professional societies. He is currently the Executive Editor of the Biomaterials Forum of the Society For Biomaterials (SFB), and President of the Institute of Biological Engineer- ing (IBE), a professional society that supports the community of scientists and engineers who are at the forefront of creating new linkages between biology and engineering and seeking new opportunities through Biology-Inspired engineering.
