Introduction to Experimental Biophysics, Second Edition: Biological Methods for Physical Scientists

Jay L. Nadeau

October 5, 2017 by CRC Press
Textbook - 764 Pages - 141 B/W Illustrations
ISBN 9781498799591 - CAT# K30594
Series: Foundations of Biochemistry and Biophysics


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• Provides a complete introduction to molecular biology techniques, including optional advanced techniques and a laboratory manual for experimental practice.

• Includes more chapter problems and questions incorporated for testing and self-study.

• Brand new chapters on gene expression techniques (microarrays, mRNA and RNA interference), and advanced techniques in biological light microscopy (two-photon microscopy to fluorescence lifetime imaging microscopy and super-resolution techniques).

• Additional chapters on holography and gold nanoparticles used in medicine.

• Gives full color presentation for several figures with an expanded glossary, updated references and supplier list.


Praise for the First Edition

“essential reading for any physical scientist who is interested in performing biological research.” ―Contemporary Physics

"an ambitious text…. Each chapter contains protocols and the conceptual reasoning behind them, which is often useful to physicists performing biological experiments for the first time." –Physics Today

This fully updated and expanded text is the best starting point for any student or researcher in the physical sciences to gain firm grounding in the techniques employed in molecular biophysics and quantitative biology. It includes brand new chapters on gene expression techniques, advanced techniques in biological light microscopy (super-resolution, two-photon, and fluorescence lifetime imaging), holography, and gold nanoparticles used in medicine. The author shares invaluable practical tips and insider’s knowledge to simplify potentially confusing techniques. The reader is guided through easy-to-follow examples carried out from start to finish with practical tips and insider’s knowledge. The emphasis is on building comfort with getting hands "wet" with basic methods and finally understanding when and how to apply or adapt them to address different questions.

Jay L. Nadeau is a scientific researcher and head of the Biomedical Engineering in Advanced Applications of Quantum, Oscillatory, and Nanotechnological Systems (BEAAQONS) lab at Caltech and was previously associate professor of biomedical engineering and physics at McGill University.