Immunological Effects of Blood Transfusion

1st Edition

Dharam P. Singal

CRC Press
Published December 8, 1994
Reference - 204 Pages
ISBN 9780849347900 - CAT# 4790

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Summary

This concise monograph examines the novel and distinct feature of blood transfusion (BT). It critically reviews the areas of major concern to the public and scientific/medical community. Topics include:
  • Transmission of disease(s) from the blood donor to the recipient and the transfusion-induced alloimmunization of the recipient
  • BT-induced immunomodulatory effects, both beneficial and deleterious
  • Beneficial effects in clinical organ transplantation and in treatment of women with unexplained recurrent abortions
  • Adverse effects of BT in patients undergoing curative surgery for different types of cancer and in patients at risk for bacterial infections
  • Deleterious effects of BT on enhanced tumor growth and infections in experimental animals
  • Attempts by a number of investigators to treat autoimmune diseases by BT in humans and in experimental animals
  • Mechanism(s) of the BT effect from various perspectives, including the component of blood, host factors, and hypotheses for beneficial and damaging effects
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