510 Pages
by
Garland Science
The story of our evolutionary past is told in our genome sequence. Human Gene Evolution deals with the origins of human genes, describes their structure, function, organisation and expression. The text integrates our emerging knowledge of chromosome and genome structure, and discusses the nature of the mutational mechanisms underlying evolutionary change.
Part 1. Introduction and Overview. 1. Structure and Function in the Human Genomes. 2. Evolution of the Human Genomes. Part 2. Evolution of Gene Structure. 3. Introns, Exons and Evolution. 4. Genes and Gene Families. 5. Promoters and Transcriptions Factors. 6. Pseudigenes and their Formation. Part 3. Mutational Mechanisms in Evolution. 7. Single Base-pair Substitutions. 8. Contractions and Expansions in Gene Size and Number. 9. Genes and Rearrangements. 10. Molecular Reconstruction of Ancient Genes/Proteins.
Biography
David N. Cooper , Institute of Medical Genetics, University of Wales College of Medicine, Cardiff, UK.
"This book containing a wealth of information, has been written by the most competent author..I have no doubt that this book is masterfully written and excellently organised, it will serve as an encyclopaedic source of information". Human Genetics 200
