Hematology

Summary

This quick reference provides the information needed to understand common and less common clinical hematology syndromes. Key concepts in hematology are broken down and simplified to create a solid, basic understanding of the fundamentals of hematology and associated clinical relevance. Each chapter addresses a particular topic in hematology and explains in an easily understood format the physiology and mechanism of common hematological conditions and relevant clinical and laboratory findings. All species are covered but, where appropriate, the hematological aspects of diseases of specific species or breeds are discussed. Important hematologic similarities and differences among small and large animal species as well as humans are emphasized. Easy to follow illustrations and over 100 multiple choice questions facilitate understanding. It is an ideal resource for veterinary students, veterinary technicians and residents and interns preparing for the board exams or as for research scientist who are considering animal models for research.

Published by Teton New Media in the USA and distributed by CRC Press outside of North America.

Table of Contents

Contents

1. Components of Blood
2. Hematopoiesis

Section I: Red Blood Cells
3. Production and Differentiation
4. Reticulocytes
5. Structure and Metabolism
6. Hemoglobin and Oxygen Transport
7. Destruction of Red Cells
8. Evaluation of Erythrocytes
9. Anemia
10. Acute Blood Loss
11. Iron Metabolism
12. Iron Deficiency Anemia
13. Hemolytic Anemia
14. Immune-mediated Hemolysis
15. Blood Group Antigens and Transfusions
16. Hemolytic Disease of the Newborn
17. Red Blood Cell Substitutes
18. Oxidative Injury to Red Cells
19. Infections Causing Hemolysis
20. Other Causes of Hemolysis
21. Nonregenerative Anemia
22. Anemia of Chronic Disease/Anemia of Inflammatory Disease
23. Anemia Secondary to Renal or Endocrine Disease
24. Folate and Cobalamin Deficiencies
25. Infectious Causes of Nonregenerative Anemia
26. Drugs, Toxins, and Metabolic Causes of Nonregenerative Anemia
27. Bone Marrow Failure
28. Polycythemia

Section II: White Blood Cells
29. Evaluation
30. Granulopoiesis (Neutrophil Production)
31. Neutrophil Structure and Function
32. Patterns of Change in Neutrophil Numbers
33. Monocytes and Macrophages
34. Eosinophils
35. Basophils and Mast Cells
36. Lymphocytes
37. Patterns of Change in Lymphocyte Numbers
38. Lymph Nodes
39. Thymus
40. Spleen

Section III: Platelets and Coagulation
41. Endothelial Cells
42. Platelets
43. Coagulation
44. Natural Anticoagulant Systems
45. Laboratory Evaluation of Hemostasis
46. Evaluation of the Bleeding Patient
47. Quantitative Platelet Disorders
48. Qualitative (Functional) Platelet Disorders
49. Inherited Clotting Factor Disorders
50. Acquired Coagulation Disorders
51. Thrombosis

Section IV: Neoplasia
52. Hematopoietic Malignancy
53. Lymphoma
54. Acute Leukemia
55. Chronic Leukemia
56. Plasma Cell Neoplasms
57. Other Hematopoietic Malignancies
58. Reference Values for Various Species
References
Questions and Answers
Index