Health Risk Assessment Dermal and Inhalation Exposure and Absorption of Toxicants

Rhoda G.M. Wang, James B. Knaak, Howard I. Maibach

August 29, 2017 by CRC Press
Reference - 544 Pages
ISBN 9781138105911 - CAT# K35056
Series: CRC Press Revivals

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Features

  • Provides new concepts that emphasize the absorbed dose and risk assessment
  • Delineates dermal absorption and tissue dose issues related to drug delivery, occupational exposure, and toxic waste site exposure
  • Emphasizes the comparative routes of exposure resulting in distinctly different dose and toxicological effects
  • Covers physiologically based pharmacokinetic modeling (PBPK) for dermal dose
  • Presents new models in skin research
  • Addresses the role epidemiology plays in assessing the hazards of toxicants
  • Summary

    Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK modeling, cytochrome P-450 metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of toxicants. Health Risk Assessment is essential for toxicologists, environmental chemists, pharmacologists, risk assessors, and managers working in industrial, pesticide, and pharmaceutical development. The book will also benefit individuals in environmental, regulatory, and registration affairs, as well as academicians and students.

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