Filled with an abundance of reader-friendly and quick-reference tables and figures, this Fourth Edition spans the etiology, epidemiology, clinical features, diagnosis, pathology, and treatment of multiple sclerosis (MS). Surpassing other texts on the topic, this reference provides recommendations and research updates from renowned authorities in the discipline and includes chapters on recent advances in neuroimaging, molecular biology, genetics, proteinomics, disease management, and combination therapy.
Table of Contents
Etiopathegenesis and Epidemiology: Clues to Etiology. Genetics: Susceptibility and Expressivity. Evidence for An Infectious Etiology. An autoimmune disease of the CNS? Clinical Features of MS. MRI Techniques in MS: Role in Diagnosis, Pathophysiology and Therapy. MS Biomarkers. Evoked Potentials. Managing the Symptoms of MS. Rehabilitation: Its Role in MS. Acute Treatments. Treatment of the Clinically Isolated Syndrome. The Use of Interferon Beta. Glatiramer Acetate. Mitoxantrone. Monoclonal Antibodies, T-Cell Receptors, and T-Cell Vaccines. Immune Therapy: Altered Peptide Ligands and Statins. Immunosuppression. Combination Therapy. Regeneration Strategies. Axonal Injury.
"...an outstanding book, providing a clear, up-to-date and well referenced account of the major advances in muscle disease."
-Neuromuscular Disorders (for previous edition)
"...present[s] the latest information concerning the immunopathology of this disease and new treatment modalities for those cursed with this affliction."
-E-Streams (for previous edition)
"…This is a valuable and scholarly book. It is heavily referenced and the reviews are filled with abundant details….highly recommended."
-Doody's Reviews (for previous edition)