Until now, no comprehensive handbook on industrial biocatalysis has been available. Soliciting chapters on virtually every aspect of biocatalysis from international experts most actively researching the field, the Handbook of Industrial Biocatalysis fills this need.
The handbook is divided into three sections based on types of substrates. The first section describes the newest biotechnology and bioprocesses for producing industrial products from hydrophobic substrates such as oils and fats. The discussion of biocatalysis covers single and multiple catalytic reactions involved in the creation of products as well as molecular manipulation of enzymes and product recovery. The products include healthy food, nutritional supplements, nutraceuticals, specialty chemicals, surfactants, biopolymers, and antimicrobial agents. The second section covers the production of value-added products from carbohydrate substrates. The scope of this section includes ethanol production, oligosaccharides and glycosides, utilization of hemicelluloses, and carbohydrate-active enzymes. The third section is dedicated to other potential industrial applications such as bioelectrocatalysis for synthesizing chemicals, fuels, and new drugs. The authors explore novel nutrition delivery systems, green chemistry, and the industrial applications of extremophiles.
The organizer of several annual worldwide symposia on biocatalysis, editor Ching T. Hou has compiled a cornerstone reference for scientists in academic, industrial, and government research institutes, as well as for graduate-level students involved in biosciences, chemical engineering, biotechnology, microbiology, oil and colloid chemistry, and food chemistry.
Table of Contents
Enzymes for the Transgenic Production of Long-Chain Polyunsaturated Fatty Acid-Enriched Oils, Y.-S. Huang, S.L. Pereira, and A.E. Leonard
Screening for Unique Microbial Reactions Useful for Industrial Applications, J. Ogawa and S. Shimizu
Biocatalyses in Microaquaeous Organic Media, T. Yamane
Biocatalysts for Epoxidation and Hydroxylation of Fatty Acids and Fatty Alcohols, Steffen C. Maurer and Rolf D. Schmid
Lipase-Catalyzed Kinetic Resolution for the Fractionation of Fatty Acids and Other Lipids, K.D. Mukherjee
Protein Engineering of Recombinant Candida rugosa Lipases, G.-C. Lee, C.-J Shieh, and J.-F. Shaw
Production of Value-Added Industrial Products from Vegetable Oils: Oxygenated Fatty Acids, C.T. Hou and M. Hosokawa
Application of Lipases to Industrial-Scale Purification of Oil-and Fat-Related Compounds, Y. Shimada, T. Nagao, and Y. Watanabe
Application of Lipases in Modification of Food Lipids, S. Sellappan and C.C. Akoh
Lipase-Catalyzed Condensation in an Organic Solvent, S. Adachi
Enzymatic Production of Diacylglycerol and Its Beneficial Physiological Functions, N. Yamada, N. Matsuo, T. Watanabe, and T. Yanagita
The Use of Nonimmobilized Lipase for Industrial Esterification of Food Oils, S. Negishi
Preparation of Polyunsaturated Phospholipids and Their Functional Properties, M. Hosokawa and K. Takahashi
Production of Biosurfactants from Fermentation of Fats, Oils, and their Co-Products, Daniel K.Y. Solaiman, R.D. Ashby, and T.A. Foglia
Fatty Acid-Modifying Enzymes: Implications for Industrial Applications, T. Aki, S. Kawamoto, S. Shigeta, and K. Ono
Low-Calorie Fat Substitutes: Synthesis and Analysis, K-T. Lee, T.A. Foglia, and J.-H. Lee
Microbial Polyunsaturated Fatty Acid Production, T. Nakahara
Structured Triacylglycerols Comprising Omega-3 Polyunsaturated Fatty Acids, G.G. Haraldsson
Biopolyesters Derived from the Fermentation of Renewable Resources, R.D. Ashby, Daniel K.Y. Solaiman, and T.A. Foglia
Carbohydrate Active-Enzymes for the Production of Oligosaccharides, H. Taniguchi
Microbial Hemicellulolytic Carbohydrate Esterases, P.Biely and G.L. Côté
Application of Cyclodextrin Glucanotransferase to the Synthesis of Useful Oligosaccharides and Glycosides, H. Nakano and S. Kitahata
Converting Herbaceous Energy Crops to Bioethanol: A Review with Emphasis on Pretreatment Processes, B.S. Dien, L.B. Iten, and C.D. Skory
Enzymes as Biocatalysts for Conversion of Lignocellulosic Biomass to Fermentable Sugars, B. Saha
Bioelectrocatalysis: Electroactive Microbial and Enzyme Technologies for Detection and Synthesis of Chemicals, Fuels, and Drugs, J.G. Zeikus
Biocatalysis: Synthesis of Chiral Intermediates for Pharmaceuticals, R.N. Patel
Nutrition Delivery System: A Novel Concept of Nutrient Fortification, T.P. Rao, N. Sakaguchi, and L.R. Juneja
Renewable Resources for Production of Aromatic Chemicals, S. Sariaslani, T. Van Dyk, L. Huang, A. Gatenby, and A. Ben-Bassat
Extremophiles from the Origin of Life to Biotechnological Applications, Chiara Schiraldi and Mario De Rosa
"This attractively produced handbook gets down to detail. It is written for teachers and specialists by active researchers, 90% from the US and the Far East, mostly from academic and government research labs, rather than production facilities."
-Tony Kirby, Chemistry & Industry, August 2006
"The text is well written and could be easily digested by readers of postgraduate level and beyond…contains a number of extremely interesting chapters in areas that are sometimes overlooked in other texts. …This book would make a good addition to research libraries and especially as a personal copy in research groups whose work focuses in biocatalysis, specifically of lipids."
-Andrew D. Brabban, Microbiology Today
"…an excellent overview of market-directed biocatalysis…the breadth of examples employing industrially useful biocatalyses makes this an exciting volume that illustrates the tools and techniques associated with the production of value-added merchandise…highly recommended for any student or professional interested in development and production of applied biocatalytic materials."
-John Williamson, SIM News, Vol. 56, No. 2, 2006
"…the book covers an area that has not been covered earlier and those interested in industrial biocatalysis - and in green chemistry - will learn a lot from many of the chapters…for those scientists working in the oils and fats industries, or in cosmetics, food and related areas, this compilation of 29 chapters will be an invaluable source of information, particularly from Japanese literature sources."
- Organic Process Research and Development, Vol. 11, No. 3, 2007