Handbook of Drug Screening

2nd Edition

Ramakrishna Seethala, Litao Zhang

CRC Press
Published June 24, 2009
Reference - 504 Pages - 100 B/W Illustrations
ISBN 9781420061680 - CAT# H1682
Series: Drugs and the Pharmaceutical Sciences

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Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery.

With extensively updated content and 21 new chapters, this text examines:

  • quality and efficiency of drug target validation and potential drug compound selection
  • reducing assay costs and improvement in assay technology
  • data quality improvement
  • trends in drug discovery
  • how drug screening can minimize adverse drug effects
  • recent advancements, including: high content screening; protein-protein interactions; high-throughput crystallization; lead optimization; chemoinformatics and microfluidics technologies; target validation by genomics, proteomics, and siRNA; structure-based drug design; automation; and medicinal chemistry


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