Gene Therapy for Neurological Disorders

Pedro R. Lowenstein, Maria G. Castro

May 1, 2006 by CRC Press
Reference - 384 Pages - 26 Color & 47 B/W Illustrations
ISBN 9780824728472 - CAT# DK3461


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Containing a 12-page color insert, this source
  • explores the applications, advantages, and limitations of the major gene therapy vectors including adenovirus, AAV, lentivirus, HSV, and non-viral vector systems
  • analyzes the brain immune response to gene therapy vectors using cutting-edge technologies
  • provides thorough analyses of human clinical trial results for several vector systems and approaches
  • covers major neurological disorders including Parkinson's disease, Alzheimer's disease, multiple sclerosis, chronic pain, and brain cancer
  • Summary

    Coedited by internationally recognized leaders in gene therapy research, this guide supplies the most recent advances, studies, and expert opinion on gene therapy for neurological disorders. Spanning conditions such as Parkinsons's and Alzheimer's disease, multiple sclerosis, brain tumors, stroke, epilepsy, and brain and spinal cord trauma, this reference presents the basic science and applications of recombinant gene products, immune and stem cell-mediated therapeutic strategies, and brain tumor gene therapy.


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