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Frontiers in Neuroscience


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Neurobiology of Huntington’s Disease: Applications to Drug Discovery

Neurobiology of Huntington’s Disease: Applications to Drug Discovery

Donald C. Lo, Robert E. Hughes
October 31, 2017

In 1993, the genetic mutation responsible for Huntington’s disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse...

Neurobiology of TRP Channels

Neurobiology of TRP Channels

Tamara Luti Rosenbaum Emir
October 10, 2017

During the last two decades, there has been an explosion of research pertaining to the molecular mechanisms that allow for organisms to detect different stimuli that is an essential feature for their survival. Among these mechanisms, living beings need to be able to respond to different...

Autism: The Movement Sensing Perspective

Autism: The Movement Sensing Perspective

Elizabeth B. Torres, Caroline Whyatt
October 03, 2017

This is the first book to present the movement approach to autism in a comprehensive way, integrating scientific methods and results with the experience of affected people, ways to improve their experiences, and the societal integration of autism....

Advances in the Neuroscience of Addiction

Advances in the Neuroscience of Addiction

Cynthia M. Kuhn, George F. Koob
September 14, 2017

Understanding the phenomenon of long-lasting vulnerability to addiction is essential to developing successful treatments. Written by an international team of authorities in their respective fields, Advances in the Neuroscience of Addiction provides an excellent overview of the available...

Translational Pain Research: From Mouse to Man

Translational Pain Research: From Mouse to Man

Lawrence Kruger, Alan R Light
September 12, 2017

One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding...

Statistical Techniques for Neuroscientists

Statistical Techniques for Neuroscientists

Young K. Truong, Mechelle M. Lewis
August 12, 2016

Statistical Techniques for Neuroscientists introduces new and useful methods for data analysis involving simultaneous recording of neuron or large cluster (brain region) neuron activity. The statistical estimation and tests of hypotheses are based on the likelihood principle derived from stationary...

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury

Daniel Laskowitz, Gerald Grant
October 09, 2015

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear...

Itch: Mechanisms and Treatment

Itch: Mechanisms and Treatment

E. Carstens, Tasuku Akiyama
February 25, 2014

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each...

Neurobiology of Chemical Communication

Neurobiology of Chemical Communication

Carla Mucignat-Caretta
February 14, 2014

Intraspecific communication involves the activation of chemoreceptors and subsequent activation of different central areas that coordinate the responses of the entire organism—ranging from behavioral modification to modulation of hormones release. Animals emit intraspecific chemical signals, often...

Neurobiology of Body Fluid Homeostasis: Transduction and Integration

Neurobiology of Body Fluid Homeostasis: Transduction and Integration

Laurival Antonio De Luca Jr., Jose Vanderlei Menani, Alan Kim Johnson
October 01, 2013

A timely symposium entitled Body-Fluid Homeostasis: Transduction and Integration was held at Araraquara, São Paulo, Brazil in 2011. This meeting was convened as an official satellite of a joint gathering of the International Society for Autonomic Neuroscience (ISAN) and the American Autonomic...

Spike Timing: Mechanisms and Function

Spike Timing: Mechanisms and Function

Patricia M. DiLorenzo, Jonathan D. Victor
May 02, 2013

Neuronal communication forms the basis for all behavior, from the smallest movement to our grandest thought processes. Among the many mechanisms that support these functions, spike timing is among the most powerful and—until recently—perhaps the least studied. In the last two decades, however, the...

Transcranial Brain Stimulation

Transcranial Brain Stimulation

Carlo Miniussi, Walter Paulus, Paolo M. Rossini
December 03, 2012

Since the discovery of transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES), these non-invasive brain stimulation (NIBS) techniques have been used to investigate the state of cortical excitability, and the excitability of the cortico-cortical and corticospinal...

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