1st Edition

Foot and Mouth Disease Current Perspectives

Edited By Francisco Sobrino, Esteban Domingo Copyright 2004
    484 Pages 64 B/W Illustrations
    by CRC Press

    The shock following the recent outbreak of foot-and-mouth disease (FMD) in the UK dispelled the notion that this disease was permanently under control and could be forgotten. FMD proved to be an endemic disease in many countries and continues to pose a major threat to animal health worldwide. The development of more effective and socially acceptable diagnosis and control measures is essential to effectively combat this devastating virus.

    Foot and Mouth Disease: Current Perspectives benefits researchers by presenting the latest developments resulting from the upsurge in data concerning this disease. Interdisciplinary in its approach, this book offers the first coherent picture of emerging strategies for diagnosis and control. With contributions from respected FMD researchers worldwide, this volume provides comprehensive coverage of the entire spectrum of FMD issues.

    Topics include genome organization, translation and replication of FMD virus RNA, proteinases, virus particles, clinical signs of FMD, and much more. This book delivers essential information for everyone with an interest in FMD, such as virologists, molecular biologists, biotechnologists, veterinarians, and pharmaceutical and biotech researchers.

    Stepping Stones in Foot-and-Mouth Research: A Personal View
    F. Brown

    Genome Organization, Translation and Replication of Foot-and-Mouth Disease Virus RNA
    Graham J. Belsham and Encarnacion Martinez-Salas

    Foot-and-Mouth Disease Virus Proteinases
    Martin D. Ryan, Michelle L.L. Donnelly, Mike Flint, Vanessa M. Cowton, Garry Luke, Lorraine E. Hughes, Caroline Knox and Pablo de Felipe

    Structure of Foot-and-Mouth Disease Virus Particles
    Cristina Ferrer-Orta and Ignacio Fita

    Clinical Signs of Foot-and-Mouth Disease
    Alex Donaldson

    Persistence of Foot-and-Mouth Disease Virus
    J.S. Salt

    Molecular Aspects of Foot-and-Mouth Disease Virus Virulence and Host Range: Role of Host Cell Receptors and Viral Factors
    Barry Baxt and Elizabeth Rieder

    Immunology of Foot-and-Mouth Disease
    Kenneth C. McCullough and Francisco Sobrino

    Functional and Structural Aspects of the Interaction of Foot-and-Mouth Disease Virus with Antibodies
    Mauricio G. Mateu and Nuria Verdaguer

    Quasispecies Dynamics and Evolution of Foot-and-Mouth Disease Virus
    Esteban Domingo, Carmen M. Ruiz-Jarabo, Armando Arias, Juan Garcia-Arriaza and Cristina Escarmis

    Modern Inactivated Foot-and-Mouth Disease (FMD) Vaccines: Historical Background and Key Elements in Production and Use
    S.J. Barteling

    Foot-and-Mouth Disease Virus Peptide Vaccines
    David J. Rowlands

    Mathematical Models of the Epidemiology and Control of Foot-and-Mouth Disease
    Mark E.J. Woolhouse

    Natural Habitats in which Foot-and-Mouth Disease Viruses are Maintained
    Wilna Vosloo and Gavin R. Thomson

    Diagnosis and Control of Foot-and-Mouth Disease
    R.P. Kitching

    Control of Foot-and-Mouth Disease: Role of International Organizations
    J. Blancou, Y. Leforban, J.E. Pearson

    Overview of Foot-and-Mouth Disease and its Impacts as a Re-Emergent Viral Infection
    Brian W.J. Mahy

    Biography

    Esteban Domingo, Francisco Sobrino

    "The relevance of this overview publication is apparent … . … [Chapters are] well-written … [and] effectively illustrated … . Additionally, the latest information gleamed from the increasing number of publications concerning this disease is offered … . … Virologists, molecular biologists, veterinarians, animal scientists, microbiologists, biotechnologists and prominently pharmaceutical and biotech researchers will find this updated review a significant insight into this increasingly concerning disease … . … A most timely publication that has global importance."
    - Vet Human Toxicol, 46 (6), Dec. 2004