Fibrinolysis in Disease: The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities

1st Edition

Pia Glas-Greenwalt

CRC Press
Published June 17, 2019
Reference - 268 Pages
ISBN 9780367244194 - CAT# K422861
Series: Routledge Revivals

USD$199.00

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Summary

First published in 1995: Fibrinolysis in Disease reviews the state of the art of basic and clinical aspects of the fibrinolytic enzyme system. The text, authored by outstanding and internationally known investigators, is presented in two books. The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities discusses the molecular biology of the system's key components and their fundamental roles in a variety of thrombotic and metabolic disorders. Molecular and Hemovascular Aspects of Fybrinolysis presents the latest findings and concepts of the association between plasminogen activator (u-PA) overexpression and abnormal growth regulation in a variety of solid tumors and in leukemia. One chapter deals with various successful interventions in thrombogenic mechanisms, ranging from exercise and diet to anticoagulants and direct and indirect thrombolytic agents. It concludes with a projection of exciting, novel treatment modalities in thrombotic and malignant diseases.

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