Evolving Neural Crest Cells

1st Edition

Brian Frank Eames, Daniel Meulemans Medeiros, Igor Adameyko

CRC Press
July 29, 2020 Forthcoming
Reference - 352 Pages - 37 Color & 1 B/W Illustrations
ISBN 9781138630819 - CAT# K32069
Series: Evolutionary Cell Biology

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Vertebrates possess lineage-specific characteristics. These include paired anterior sense organs and a robust, modular head skeleton built of cellular cartilage and bone. All of these structures are derived, at least partly, from an embryonic tissue unique vertebrates - the neural crest. The evolutionary history of the neural crest, and neural crest cells, has been difficult to reconstruct. This volume will use a comparative approach to survey the development of the neural crest in vertebrates, and neural crest-like cells, across the metazoa. This information will be used to reveal neural crest evolution and identify the genomic, genetic, and gene-regulatory changes that drove them.


Key selling features:

  • Summarizes the data regarding neural crest cells and nerural crest derivatives
  • Uses a broad-based comparative approach
  • Suggests hypothesis that the origin of neural crest cells involved the novel co-activation of ancient metazoan gene programs in neural border cells
  • Illustrates how the emergences of neural crest made possible the diversification of vertebrate heads
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