Chester A. Glomski, Alessandra Pica, Jessica F. Greene
Published December 22, 2015
Reference - 254 Pages - 47 B/W Illustrations
ISBN 9781498733595 - CAT# K26316
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Erythrocytes of the Rhesus and Cynomolgus Monkeys addresses the morphologic, quantitative, and generative aspects of the erythrocytes of the rhesus monkey Macaca mulatta and the cynomolgus monkey Macaca fascicularis (long-tailed macaque, crab-eating monkey). These two species are the most commonly selected nonhuman primates for basic science and clinical medical investigations.
The hemopoietic cells of man and the rhesus monkey display an intimate homogeneity. Their functional activities are close and at times identical. The cynomolgus monkey was enlisted in biomedical studies at a time when rhesus monkeys were not available in sufficient quantities. It has gained increased use in the Far East and in the Western world. It is, for example, employed in the current development of a vaccine against the deadly Ebola virus.
The authors of the book discuss the erythropoietic profiles of normal and abnormal macaques of both sexes and of all age groups as investigated with contemporary electronic methodologies. They cover the role of stress as it is perceived by the monkey and how it impacts erythrocellular values, and how to train the monkey to be a cooperative, unperturbed subject for hematologic study. Additional topics include the role of medication in deriving normal physiologic erythrocellular data, the development of the precursors of the erythrocyte (normoblasts), the morphologic analysis of the megaloblastic series of abnormal erythroid cells, the analysis of erythropoiesis in bone marrow, the relationship of the simian immunodeficiency virus and erythropoiesis, erythrocyte life span, and parasitic invasion of the red cell.
Pursuit of the Baseline, Steady State Hemograms of Macaca mulatta and Macaca fascicularis
Stress and the Erythrogram
Ketamine: Its Use in Obtaining Erythroid Values of Blood
Training Rhesus Monkeys to Voluntarily Cooperate in Obtaining Phlebotomies
Bone Marrow: Erythropoiesis
Bone Marrow: Erythrogram
Erythrocyte Life Span
Erythrocyte-Based Values and Gender Relationships
Erythrocyte Indices (MCV, MCH, MCHC)
Erythrogram: Variability Associated with Age
Effects of Fasting on the Erythrogram of Macaca fascicularis
Erythrogram of Infant Macaca mulatta
Erythroid Profile of Fetal Macaca fascicularis
Erythrogram of Infant Macaca fascicularis
Simian Immunodeficiency Virus (SIV): Its Relationship with Erythropoiesis in Macaca mulatta
Erythroid Profile of Pregnant Macaca mulatta
Erythroid Profile of Pregnant Macaca fascicularis
Erythrocytes and the Menstrual Cycle
Anemia due to Deprivation of Dietary Protein
Feral Anemic Cohort in Sumatra
Malaria and Babesiosis
Hemolytic Uremic Syndrome
Vitamin E Deficiency
Experimentally Induced Autoimmune Hemolytic Anemia
ABO Blood Group System
Alphabetical Index of investigators’ Reports Listed in Table 1 (Superscripts are those utilized in Table 1)
"Erythrocytes of the Rhesus and Cynomolgus Monkeys is a text that addresses the morphologic, quantitative, and generative aspects of erythrocytes of the rhesus monkey Macaca mulatta and the cynomolgus monkey Macaca fascicularis (long-tailed macaque, crab-eating monkey). These two species are the most commonly selected nonhuman primates for biomedical scientific investigations. ...
The book includes many useful tables, drawings and images to illustrate important concepts in erythrocyte science. It also includes a useful meta-analysis of normative ranges in tables toward the end of the book. These tables are organized by species and include the references from which the erythrocyte data ranges are extracted. …
Overall, the text does provide a valuable reference and resource for non-human primate scientists and veterinarians. I would recommend this book especially for investigators who study erythrocyte biology and diseases of red blood cells."
Dr. Diana Scorpio, DVM, MPH, DACLAM (Vaccine Research Center, National Institutes of Health, Bethesda MD) in Laboratory Animal Practitioner