Filling a gap in the literature, this guide analyzes EBV infection and all of its associated disorders including infectious mononucleosis, Burkitt lymphoma, and Hodgkin's disease. Opening with a historical introduction, the reference progresses from molecular virology, epidemiology, immunology, and pathology to clinical presentation, diagnosis, disease detection, patient management, and vaccine development.
Table of Contents
The History of Epstein-Barr Virus. Virology and Molecular Biology of Epstein-Barr Virus. Epidemiology of the Epstein-Barr Virus and Infectious Mononucleosis. Pathology of Primary and Persistent EBV Infection. The Immune Response to Epstein-Barr Virus. Clinical Features of Infectious Mononucleosis. Epstein-Barr Virus Disease: Serologic and Virologic Diagnosis. Epstein-Barr Virus and the Nervous System. Epstein-Barr Virus Infection in AIDS. Burkitt's Lymphoma. Hodgkin's Disease. Posttransplant Lymphoproliferative Disease. T-cell Lymphomas Associated with EBV. Nasopharyngeal Carcinoma. Leiomyosarcoma. X-linked lymphoproliferative Syndrome. Diseases Possibly Associated with EBV. Treatment of Epstein-Barr Virus Infection. Development of Epstein-Barr Virus Vaccines
"…we should congratulate the editors of this book both for its conception and for assembling a group of internationally recognized experts to review the current state of knowledge of EBV infection…a welcome addition to the bookshelves of any teaching institution or clinical virology laboratory."
-Clinical Infectious Diseases
"…I very much enjoyed this book and will be happy to refer to it. I especially appreciated the historical review of the discovery of EBV and the contributions of Denis Burkitt. Each chapter is heavily referenced with relatively current references. The chapters read well and were obviously well edited."
"…This excellent and concise book covers it all. It has chapters that span the history and discovery of the virus through its virology and molecular biology up through the interactions that lead to the normal non-pathogenic infection in humans….an excellent book."