Enzymology of Complex Glycans

1st Edition

Martin Steup, Felix Nitschke

CRC Press
January 15, 2020 Forthcoming
Reference - 340 Pages
ISBN 9781138505209 - CAT# K39523

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Summary

In all living systems various polyglycans exist having essential functions that are closely linked to glycan structures. All structural features of glycans are mediated by kinetic properties of glycan synthesizing enzymes. Often, glycan-related enzymes non-covalently bind to the carbohydrate substrate(s) by regions different from the active site. Removal of these binding sites often strongly affect carbohydrate specifics of the enzyme. This book describes recent progress in polyglycan-related enzymology. It covers kinetic features of enzymes and reactions, metabolic paths, the reversible formation of glycan-related enzyme complexes, and procedures used for structural analyses of polyglycans.

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