Engineering 3D Tissue Test Systems

Karen J.L. Burg, Didier Dréau, Timothy Burg

© 2018 - CRC Press
Published July 27, 2017
Reference - 412 Pages - 68 Color & 28 B/W Illustrations
ISBN 9781138745674 - CAT# K32422

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  • Offers a brief introduction of tissue test systems and their translation to the research, industrial, and medical communities
  • Outlines the common and specific functional requirements for tissue test system applications
  • Describes biofabrication methods and best practices
  • Discusses specific tissue test system applications, including liver, breast, bone, and tumor
  • Covers a broad range of topics, including polymers for specific tissue test system applications, interactions between test system biomaterials and cellular components, and test system validation
  • Organized into three main topics: instrumentation to build and house 3D systems, issues surrounding biomaterials, and biological issues and overall system considerations
  • Includes a chapter on regulatory and pricing issues


Engineering 3D Tissue Test Systems provides an introduction to, and unique coverage of, a rapidly evolving area in biomaterials engineering. It reveals the current and future research responses, the current and future diagnostic applications, and provides a comprehensive overview to foster innovation. It offers insight into the importance of 3D systems and their use as benchtop models, spanning applications from basic scientific research to clinical diagnostics. Methods and limitations of building 3D tissue structures are evaluated, with attention given to the cellular, polymeric, and fabrication instrumentation components. The book covers the important aspects of polymeric tissue test systems, highlighting the needs and constraints of the industry, and includes a chapter on regulatory and pricing issues.


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