Endotoxins: Pyrogens, LAL Testing and Depyrogenation

3rd Edition

Kevin L. Williams

CRC Press
Published February 23, 2007
Reference - 440 Pages - 85 B/W Illustrations
ISBN 9780849393723 - CAT# DK9372
Series: Drugs and the Pharmaceutical Sciences

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Summary

This source expertly examines the discovery, biological structure, control, and continued clarification of endotoxin from a parenteral manufacturing perspective, with in-depth discussion of state-of-the-art technologies involving Limulus amebocyte lysate (LAL) such as assay development, automation, depyrogenation.  Completely revised and expanded, this Third Edition contains the knowledge necessary to apply endotoxin testing in the increasingly complex pharmaceutical environment, featuring sections detailing the latest information regarding clinical advances, regulation standards, and validation procedures for computerized kinetic tests.

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