1st Edition

Electrokinetic Particle Transport in Micro-/Nanofluidics Direct Numerical Simulation Analysis

By Shizhi Qian, Ye Ai Copyright 2012
    398 Pages 197 B/W Illustrations
    by CRC Press

    Numerous applications of micro-/nanofluidics are related to particle transport in micro-/nanoscale channels, and electrokinetics has proved to be one of the most promising tools to manipulate particles in micro/nanofluidics. Therefore, a comprehensive understanding of electrokinetic particle transport in micro-/nanoscale channels is crucial to the development of micro-/nanofluidic devices.

    Electrokinetic Particle Transport in Micro-/Nanofluidics: Direct Numerical Simulation Analysis provides a fundamental understanding of electrokinetic particle transport in micro-/nanofluidics involving electrophoresis, dielectrophoresis, electroosmosis, and induced-charge electroosmosis. The book emphasizes the direct numerical simulation of electrokinetic particle transport phenomena, plus several supportive experimental studies. Using the commercial finite element package COMSOL Multiphysics®, it guides researchers on how to predict the particle transport subjected to electric fields in micro-/nanoscale channels.

    Researchers in the micro-/nanofluidics community, who may have limited experience in writing their own codes for numerical simulations, can extend the numerical models and codes presented in this book to their own research and guide the development of real micro-/nanofluidics devices.

    Corresponding COMSOL® script files are provided with the book and can be downloaded from the author’s website.

    Basics of Electrokinetics in Micro/Nano-fluidics
    Introduction to Micro/Nano-fluidics
    Particle Transport and Manipulation in Micro/Nano-fluidics
    Basics of Electrokinetics
    Organization of this Book

    Numerical Simulations of Electrical Double Layer and Electroosmotic Flow in a Nanopore
    Electrical Double Layer
    Electroosmotic Flow in a Nanopore
    Concluding Remarks

    Transient Electrokinetic Motion of a Circular Particle in a Microchannel
    Introduction
    Mathematical Model
    Numerical Implementation in COMSOL®
    Results and Discussion
    Concluding Remarks

    Electrokinetic Transport of Cylindrical-Shaped Cells in a Straight Microchannel
    Introduction
    Experimental Setup
    Mathematical Model
    Numerical Implementation in COMSOL®
    Results and Discussion
    Concluding Remarks

    Shear- and Electrokinetics-Induced Particle Deformation in a Slit Channel
    Introduction
    Shear-Induced Particle Deformation
    Electrokinetic-Induced Particle Deformation
    Concluding Remarks

    Pair Interaction between Two Colloidal Particles under DC Electric Field
    Introduction
    Mathematical Model
    Numerical Implementation in COMSOL®
    Results and Discussion
    Concluding Remarks

    Electrokinetic Translocation of a Cylindrical Particle through a Nanopore: Poisson–Boltzmann Approach
    Introduction
    Mathematical Model
    Numerical Implementation in COMSOL® and Code Validation
    Results and Discussion
    Concluding Remarks

    Electrokinetic Translocation of a Cylindrical Particle through a Nanopore: Poisson–Nernst–Planck Multi-ion Model
    Introduction
    Mathematical Model
    Numerical Implementation in COMSOL® and Code Validation
    Results and Discussion
    Concluding Remarks

    Field Effect Control of DNA Translocation through a Nanopore
    Introduction
    Mathematical Model
    Implementation in COMSOL Multiphysics® and Code Validation
    Results and Discussion
    Concluding Remarks

    Electrokinetic Particle Translocation through a Nanopore Containing a Floating Electrode
    Introduction
    Mathematical Model
    Implementation in COMSOL Multiphysics®
    Results and Discussion
    Concluding Remarks

    Biography

    Shizhi Qian, Ye Ai