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Written by internationally known European and American scientists, these volumes systematically present many topics in the elastin and elastases fields. Volume I explains elastin, its biosynthesis, physicochemical properties, and alteration in a variety of pathologies and with aging. Volume II describes elastases, their physiological and pathological roles and their control by natural and synthetic inhibitors. Filled with illustrations and figures, these volumes will benefit researchers, physicians, and industrial scientists.
Table of Contents
Volume II ELASTASES: MECHANISMS OF ACTION Mechanisms Involved in Elastin-Elastase Interaction Mechanism of Action of Elastases ELASTASES: CHARACTERIZATION AND BIOLOGICAL ROLES Human Neutrophil Elastase Human Platelet-Derived Elastase (EC-3-4-21) Macrophage Elastase Aortic Elastase Fibroblast Elastase(s) On the Nature of the Elastase Activity of Human Serum Pseudomonas aeruginosa Elastase BIOLOGICAL CONTROL OF ELASTOLYSIS AND THERAPEUTIC USE OF ELASTASE INHIBITORS Control of Elastolysis by Elastase Inhibitors: Kinetic Aspects Properties of Naturally Occurring Elastase Inhibitors Design and Properties of Synthetic Elastase Inhibitors Targeted Bifunctional Elastase Inhibitors Properties and Therapeutic Potential of Eglin C ELASTIN AND ELASTASES IN PATHOLOGY Ultrastructure of Elastic Fibers in Pathology Elastin and Elastases in Lung Disease Elastin and Elastases in the Pathology of the Arterial Wall Elastin and Elastic Fibers in Normal and Pathological Skin: Modifications with Aging Elastin in Human Breast Tumors Neosynthesis of Elastin in Response to Vascular Injury The Temporal Arteritis/Polymyalgia Rheumatica Syndrome Bovine Elastin a, b, and c Index
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