ESMO Handbook on Principles of Translational Research

1st Edition

Håkan Mellstedt, Dirk Schrijvers, Dimitrios Bafaloukos, Richard Griel

CRC Press
Published May 21, 2007
Reference - 176 Pages
ISBN 9780415410915 - CAT# DU0916
Series: European Society for Medical Oncology Handbooks

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Summary

Using state-of-the-art and evidence-based literature references and reviews, the authors present an overview of translational research that is both reliable and easily understood. The book begins with principles of normal cell biology and normal immunology. It examines tumor biology and basic tumor immunology. It then discusses limitless replicative potential, self-sufficiency in growth signals, insensitivity to anti-growth signals, and evading apoptosis. The book concludes with a chapter on angiogenesis, tissue invasion and metastasis, treatment, and evaluation of treatment.

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