210 Pages
    by CRC Press

    Cancer is a disease related to ageing, and the proportion of senior patients increases worldwide. While the proportion of persons beyond age 70 is still small in developing countries, their numerous population means that there are more "elderlies" in India than in Europe. This book reflects the state of the art in the management of senior adults with cancer. This handbook leaves ample space for chapters that help in the delicate decisionmaking process, which should lead to the best therapy, adapted not only to the disease but also to the person who suffers from it.

    Introduction
    Defining the Elderly
    Biology of Aging and Changes in Organ Function
    Changes in Cognition
    Cancer and Aging
    Clinical Aspects
    Further Reading

    Cancer Epidemiology
    Introduction
    Population Demographics
    Cancer Demographics
    Society-Related Problems
    Conclusions
    Further Reading

    Evaluation of the Senior Cancer Patient: Comprehensive Geriatric Assessment and Screening Tools for the Elderly
    Introduction
    Short Screening Tools
    The Vulnerable Elders Survey 13
    MGA Packages
    Further Reading

    Frailty in the Elderly
    Frailty in the Elderly
    The Impact of Frailty on Cancer
    Assessment of Frailty
    Conclusion
    Further Reading

    Surgical Treatment
    Introduction
    Indications for Surgery
    Patients Selection
    Outcomes
    Survival
    Palliation
    Side Effects
    Conclusion
    Further Reading

    Radiotherapy in the Elderly Cancer Patient
    Indications for Radiotherapy in the Elderly
    Side Effects of Radiotherapy in the Elderly (Acute and Late)
    Efficacy and Outcome of Radiotherapy in the Aging
    Palliative Setting: Toxicity and Efficacy Ratio
    Curative Setting: Combinations of Chemotherapy and Radiotherapy
    Selection Criteria for Radiotherapy in the Elderly
    Conclusions
    Further Reading

    Hormonal Anticancer Treatment in the Senior Cancer Patient
    Introduction
    Breast Cancer
    Prostate Cancer
    Further Reading

    Cytotoxic and Targeted Anticancer Treatment in the Senior Cancer Patient
    Introduction
    Chemotherapy in Senior Adults
    Targeted Therapies in Senior Adults
    Further Reading

    Treatment of Lymphoma in the Elderly Population
    Introduction
    Diagnosis and Prognosis
    Treatment
    Conclusions
    Further Reading

    Management of Myeloproliferative Diseases in Senior Patients
    Diagnosis and Classification of Myeloproliferative Disorders
    Treatment Strategies of MPD in the Senior Patient
    Conclusions
    Future Outlook
    Further Reading

    Myelodysplastic Syndromes in the Senior Patient
    The Relevance of Myelodysplastic Syndromes in the Elderly
    Classification and Risk Scoring in MDS
    Age-Adjusted Models and Assessment in Elderly MDS Patients
    Treatment Options in Elderly MDS Patients
    Future Perspectives
    Further Reading

    Breast Cancer in the Senior Patient
    Introduction
    Early Breast Cancer
    Metastatic Breast Cancer
    Conclusions
    Further Reading

    Lung Cancer in the Elderly
    Introduction
    Early Non–Small Cell Lung Cancer in the Elderly
    Advanced Non–Small Cell Lung Cancer in the Elderly
    Small Cell Lung Cancer in the Elderly
    Palliative Treatment in Elderly Lung Cancer Patients
    Conclusion
    Further Reading

    Colorectal Cancer
    Introduction
    Adjuvant Chemotherapy
    Metastatic Disease
    Conclusion
    Further Reading

    Prostate Cancer
    Introduction and General Background
    Treatment of Localized Prostate Cancer in Senior Adult Patients
    Treatment of Metastatic Prostate Cancer in Senior Adult Patients
    Conclusion
    Acknowledgments
    Further Reading

    Bladder Cancer
    Incidence and Mortality
    Etiology and Risk Factors
    Pathology
    Natural History and Tumor Biology
    Signs and Symptoms
    Imaging, Cystoscopy, and Urinary Cytopathology
    Staging
    Treatment of NMIBC
    Surgical Treatment
    Radiotherapy
    Organ-Sparing Treatments
    Systemic Chemotherapy
    Prognosis of BC
    Follow-Up
    Further Reading

    Gynecological Cancer in the Senior Patient
    Introduction
    Cervical Cancer
    Uterine Cancer
    Special Types of Endometrial Malignancy
    Vaginal Cancer
    Vulvar Cancer
    Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
    Conclusion
    Further Reading

    Head and Neck Cancer in the Elderly
    Introduction
    Surgery
    Radiotherapy
    Chemotherapy
    Targeted Therapies
    Conclusion
    Further Reading

    Renal Cell Cancer
    Introduction
    Surgery in the Senior Cancer Patient
    Systemic Therapy of Metastatic Renal Cell Carcinoma in the Senior Cancer Patient
    Patient-Focused Approach
    Conclusion
    Further Reading

    Psychological Problems in Older Cancer Patients
    Introduction
    Depression
    Anxiety
    Conclusions
    Further Reading

    Social and Ethical Aspects
    Introduction
    Respect
    Admiration
    Attention
    Information
    Protection
    Diagnosis
    Care
    Time
    Caution
    Freedom
    Further Reading

    The Role of the Multidisciplinary Team
    Introduction
    The Assessment of Age
    Polypharmacy
    Management of the Caregiver
    Function of the Team
    Conclusions and Perspectives
    Further Reading

    Biography

    Dirk Schrijvers, Matti Aapro, Branko Zakotnik, Riccardo Audisio, Hendrik van Halteren, Hurria Arti