Delivery Strategies for Antisense Oligonucleotide Therapeutics

Saghir Akhtar

July 13, 2017 by CRC Press
Reference - 320 Pages
ISBN 9781138505896 - CAT# K39554
Series: CRC Press Revivals


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  • The first book to focus solely on the delivery of antisense nucleic acids
  • Contributions from leading scientists in the antisense field
  • Review-type articles to introduce newcomers to the field
  • Review-type articles linked with exciting previously unpublished data on delivery of antisense therapeutics
  • Information on the state-of-the-art strategies for improved cellular and tissue delivery of antisense, antigene, and ribozyme nucleic acids
  • 134 illustrations and tables
  • Summary

    With contributions from leading experts, this book is the first to focus solely on addressing the problems and reviewing the strategies currently being used to improve the delivery of antisense nucleic acids. Important delivery issues, such as improving biological stability, improving cell-specific targeting and cellular uptake, manipulating subcellular distribution and producing liposomal delivery systems for antisense agents are comprehensively covered in this volume. This book links review-type articles with contributions that contain exciting never-before-published data on the cellular delivery of oligonucleotides. It stimulates reading for both established researchers and newcomers to the antisense field.


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