Cory Douglas Bishop, Brian K. Hall
November 26, 2019 Forthcoming
Reference - 328 Pages - 20 Color & 30 B/W Illustrations
ISBN 9781138334281 - CAT# K393323
Series: Evolutionary Cell Biology
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This volume examines cells set-aside during development for use later in ontogeny or in adult life. There is no single term for such cells. The cells explored fall with several major categories — stem cells, set-aside cells (in echinoderm larvae), imaginal discs in insects such as Drosophila, meristems (plants), blastemata (regeneration in amphibians), neoblasts (regeneration in planarians). The book compares and contrasts these cells types and the environments (niches) in which they operate with the aim of unravelling any relationships between them, between their activation in development, and in their evolution.
Calegari, F. & C. Waskow, eds. Stem Cells: From Basic Research to Therapy (ISBN 978-1-4822-0775-0)
Cabral, J. M. S. & C. L. da Silva, eds. Bioreactors for Stem Cell Expansion and Differentiation (ISBN 978-1-4987-9590-6)
Section I Deferred-use Cells in Development and Evolution. Deferred-use cells/niches: Evolutionary -life history perspective chapter. Deferred-use cells/niches: Developmental mechanisms chapter. Section II Phylogenetic overview of types of deferred-use cells and their niches. Stem cells and stem cell niches in animals: Classic example of life long multipotential cells. Deferred-use cells and niches in Fungi, lichens, mosses. Meristems and niche in plants. Set-aside cells (juvenile rudiments) and their niches in echinoderms. multipotential cells in embryos/larvae with metamorphosis. Imaginal disc cells and their niches in insects (Drosophila): Determined cells specified for individual parts of the adult body. Blastemal cells and neoblasts in amphibian and planarian regeneration. Section III Origin and evolution of deferred-use cells. Deferred-use cells in non-bilaterian animals (cnidarians, ctenophores) and in choanoflagellates and the evolutionary origin of deferred-use cells in animals. Deferred-use cells and the evolution of complexity, complex life cycles, direct/indirect development and response of deferred-use cells to selection. Deferred-use cells, germ cells and gametes, separation of germ line and soma. Deferred-use cells, and the evolution of phenotypic plasticity, life history stages and control of body size. Section IV Mechanisms of maintenance/activation of deferred-use cells during ontogeny. The role of cell cycle/mitosis in the evolution of deferred-use cells. Deferred-use cells and regulation of cell differentiation, de- and redifferentiation. Cancer and stem-cell related diseases as the cost of having deferred-use cells. Genetic and epigenetic control of deferred-use cells and their niches: Hippo pathway and mechanical factors in imaginal discs as major examples but with comparisons among model systems. Hormonal and metabolic regulation of maintenance/activation of deferreduse cells and their niches. Section V Overview and Future prospects. Overview and summary of the cells and niches, molecular control, phylogenetic history and evolution.