Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases

1st Edition

James Devillers

CRC Press
Published January 4, 2018
Reference - 468 Pages - 15 Color & 315 B/W Illustrations
ISBN 9781498741804 - CAT# K26763
Series: QSAR in Environmental and Health Sciences

For Instructors Request Inspection Copy

was $239.95

USD$191.96

SAVE ~$47.99

Add to Wish List
FREE Standard Shipping!

Summary

There is a compelling need for new drugs and efficient treatments against mosquito-borne diseases. Environmentally safe, but effective insecticides that address the problems of resistance are required. Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases explains how the search for new substances effective against mosquitoes and their diseases has benefited from the use of in silico techniques. QSAR modeling is suited to identify the key structural features and/or physicochemical properties explaining an activity and to propose candidate molecules for further evaluation by laboratory tests. Homology modeling is useful to approximate the 3D structure of proteins of interest. Pharmacophore modeling is a powerful means to capture the chemical features responsible for an activity and to identify new potentially active compounds via the virtual screening of databases. Fugacity modeling and a wealth of other modeling paradigms are useful for risk assessment in vector borne disease control.

Instructors

We provide complimentary e-inspection copies of primary textbooks to instructors considering our books for course adoption.

Request an
e-inspection copy

Share this Title