1st Edition

Colloids in Drug Delivery

Edited By Monzer Fanun Copyright 2010
    652 Pages 179 B/W Illustrations
    by CRC Press

    652 Pages 179 B/W Illustrations
    by CRC Press

    Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research in the field, Colloids in Drug Delivery assembles the work of 65 of the world’s leading colloid scientists who examine the full spectrum of this rapidly emerging science, from pure to applied, most of it drawn from their own experience and research.

    The book begins by examining the basics of surfactant and polymer surface activity and self-assembly, the various types of structures formed by such compounds, and their use in drug delivery and biotechnology. It examines the development of controlled and targeted delivery systems by utilizing the various properties of colloids before moving on to discuss various applications and fields of research.

    Topics discussed include:

    • The use of hard, soft, and macromolecular colloidal drug delivery systems formed by surfactants, polymers, proteins, and lipids
    • Recent advances in procolloidal systems, self-emulsifying drug delivery systems, and aerosol applications to pharmaceutical drug delivery
    • Colloidal nanocarriers for imaging applications and the treatment of dental and periodontal diseases
    • Classification and application of colloidal drug delivery systems in tumor targeting
    • The use of colloids for improved nasal, ocular, vaginal, oral, buccal, gastrointestinal, and colon drug delivery

    Examining topics necessary to the critical evaluation of a drug candidate’s potential for delivery, the book also describes the preparation, classification, interfacial activity, surface modifications and influence on particle characteristics, drug delivery, and drug targeting. Each chapter in this expansive volume explains why a particular system is used for the intended application, how it is made, and how it behaves.

    All those concerned with the research, development, and manufacture of drugs will find this a valuable reference, offering a wealth of research upon which they can build.

    Surfactants and Block Copolymers in Drug Delivery; A. Misra, K. Florence, M. Lalan, and T. Shah

    Application of Colloidal Properties in Drug Delivery; S. Saraf

    Polymeric Nanocapsules for Drug Delivery: An Overview; S. S. Guterres, F. S. Poletto, L. M. Colomé, R. P. Raffin, and A. R. Pohlmann

    Poly(Alkyl Cyanoacrylate) Nanoparticles for Drug Delivery and Vaccine Development; A. Graf, K. Krauel-Göllner, and T. Rades

    Stimuli-Sensitive Polymer Gels for Dermal and Transdermal Drug Delivery and Their Application in the Development of Smart Textile Materials; W. Musial and V. Kokol

    Micelles: The Multifunctional Nanocarrier for Colloidal Drug Delivery; C. Mohanty, S. Acharya, and S. K. Sahoo

    Multiple Emulsions: An Overview and Pharmaceutical Applications; J. Khurana, S. Singh, and A. K. Dash

    Pharmaceutical and Biotechnological Applications of Multiple Emulsions; R. Cortesi and E. Esposito

    Nanoemulsions as Drug Delivery Systems; F. Tirnaksiz, S. Akkus, and N. Celebi

    Microemulsion Systems: Application in Delivery of Poorly Soluble Drugs; L. Djekic and M. Primorac

    Diclofenac Solubilization in Mixed Nonionic Surfactants Microemulsions; M. Fanun

    Self-Emulsifying Drug Delivery Systems; D. P. Maurya, Y. Sultana, and M. Abul Kalam

    Liquid Crystals and Their Application in the Field of Drug Delivery; R. Patel and T. N. Patel

    Liquid Crystalline Nanoparticles as Drug Nanocarriers; A. Yaghmur and M. Rappolt

    Niosomal Delivery System for Macromolecular Drugs; Y. Huang, F. Yu, and W. Liang

    A New Class of Mesoscopic Aggregates as a Novel Drug Delivery System; F. Bordi, C. Cametti, and S. Sennato

    Liposomes and Biomacromolecules: Effects of Preparation Protocol on In Vitro Activity; P. Luciani, D. Berti, and P. Baglioni

    Colloidal Nanocarrier Systems as a Tool for Improving Antimycobacterial and Antitumor Activities and Reducing the Toxicity of Usnic Acid; N. S. Santos-Magalhães, N. P. S. Santos, M. C. B. Lira, M. S. Ferraz, E. C. Pereira and N. H. Silva

    Dendrimers in Drug Delivery; H. Yang

    Microsphere: A Novel Drug Delivery System; A. Samad, M. Tariq, M. I. Alam, and M. S. Akhter

    Colloids in Aerosol Drug Delivery Systems; N. Islam

    Respiratory Aerosol Dynamics with Applications to Pharmaceutical Drug Delivery; J. Xi, P. Worth Longest, and P. J. Anderson

    Colloidal Carriers for Drug Delivery in Dental Tissue Engineering; N. Kalaji, N. Sheibat-Othman, and H. Fessi

    Classification and Application of Colloidal Drug Delivery Systems: Passive or Active Tumor Targeting; H. Yesim Karasulu, B. Karaca, and E. Karasulu

    Nanocarriers for Imaging Applications; V. Patravale and M. Joshi

    Index

    Biography

    Monzer Fanun is a member of the faculty of Science and Technology at Al-Quds University.