Ding-Geng (Din) Chen, Karl E. Peace, Pinggao Zhang

May 3, 2017
by Chapman and Hall/CRC

Reference
- 378 Pages
- 100 B/W Illustrations

ISBN 9781498779524 - CAT# K29875

Series: Chapman & Hall/CRC Biostatistics Series

USD^{$}119^{.95}

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- No previous experience in R/SAS is needed.
- Presents real clinical trials with associated clinical data
- Provides step-by-step approach using R/SAS to analyze clinical trial data
- Features new chapters, new datasets and SAS coverage

Review of the First Edition

*"The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and does a nice job. I would highly recommend it …The example-based approach is easy to follow and makes the book a very helpful desktop reference for many biostatistics methods."***— Journal of Statistical Software**

**Clinical Trial Data Analysis Using R and SAS, Second Edition** provides a thorough presentation of biostatistical analyses of clinical trial data with step-by-step implementations using R and SAS. The book’s practical, detailed approach draws on the authors’ 30 years’ experience in biostatistical research and clinical development. The authors develop step-by-step analysis code using appropriate R packages and functions and SAS PROCS, which enables readers to gain an understanding of the analysis methods and R and SAS implementation so that they can use these two popular software packages to analyze their own clinical trial data.

What’s New in the Second Edition

- Adds SAS programs along with the R programs for clinical trial data analysis.
- Updates all the statistical analysis with updated R packages.
- Includes correlated data analysis with multivariate analysis of variance.
- Applies R and SAS to clinical trial data from hypertension, duodenal ulcer, beta blockers, familial andenomatous polyposis, and breast cancer trials.
- Covers the biostatistical aspects of various clinical trials, including treatment comparisons, time-to-event endpoints, longitudinal clinical trials, and bioequivalence trials.