1st Edition

Chemotherapy for Gynecological Neoplasms Current Therapy and Novel Approaches

    Compiling an authoritative collection of research, recommendations, and guidelines from a highly regarded team of experts, this reference promotes a clear understanding of the chemotherapeutic management of cancer in each organ site of the lower female genital tract including the ovaries, fallopian tubes, uterus, vulva, and vagina.

    Preface I. Basic Principles of Chemotherapy1. Antineoplastic Agents: Classification and Mechanisms of Action 2. Mechanisms of Chemosensitivity and Resistance 3. In Vitro Testing for Drug Sensitivity/Resistance 4. Basic Principles of Dose Intensity and High-Dose Chemotherapy 5. Immunotherapy in Gynecologic Malignancies 6. Gene Therapy of Ovarian Cancer 7. Basic Concepts of Chemotherapy Sequence and Combinations 8. Pharmacoeconomic Applications in Gynecologic Oncology II. Clinical Aspects of Chemotherapy 9. Guidelines to Writing a Clinical Protocol 10. Evaluation of Gynecologic Tumor Response: When and How? 11. Practical Guide on How to Deliver Chemotherapy 12. Evaluation of the Patient for Chemotherapy 13. Chemotherapy in Pregnancy 14. Supportive Treatment in Gynecologic Malignancies 15. Hormone Replacement Therapy in Gynecologic Cancer Patients and Survivors 16. Infections in Patients with Gynecological Malignancies: Prevention and Management 17. Pharmacologic Pain Management in Gynecologic Oncology 18. Blood Transfusion During Chemotherapy: Risks and Benefits 19. Role of Tumor Markers in Gynecologic Oncology 20. Role of Chemoprotectors During Chemotherapy for Gynecologic Neoplasms 21. Chemoprevention in Gynecological Oncology 22. Role of Psychological Support During Chemotherapy 23. Quality of Life During Chemotherapy: Recent Results and Methodological Challenges of Conducting Quality-of-Life Studies with Gynecological Cancer Patients III. Ovarian Cancer 24. Ovarian Cancer 25. Management of Early Epithelial Ovarian Cancer 26. Chemotherapy for Advanced Primary Epithelial Ovarian Cancer: Neoadjuvant and Adjuvant 27. Persistent and Recurrent Ovarian Cancer 28. Intraperitoneal Chemotherapy: Basic Concepts and Clinical Trials 29. Chemotherapy for Germ Cell Tumors 30. Chemotherapy for Sex Cord–Stromal Tumors 31. Ovarian Cancer: Rationale and Strategies Beyond First-Line Treatment IV. Fallopian Tubes 32. Fallopian Tube Cancer 33. Chemotherapy of Fallopian Tube Cancer 34. Endometrial Cancer 35. Medical Therapy for Endometrial Hyperplasia and Early Endometrial Cancer in Patients Desiring Future Childbearing 36. Uterine Carcinomas: Chemotherapy for Primary and Recurrent Tumors 37. Chemotherapy in Uterine Mesenchymal Tumors VI. Cervix 38. Cervical Cancer 39. Neoadjuvant Chemotherapy in Cervical Cancer 40. Chemoradiation Therapy for Cervical Cancer 41. Chemotherapy for Recurrent and Advanced Cervical Cancer VII. Vulva and Vagina 42. Vulvar Cancer 43. Chemotherapy in Vulvar Cancer 44. Vaginal Cancer 45. Vaginal Cancer Chemotherapy VIII. Gestational Trophoblastic Disease 46. Management of Hydatidiform Mole 47. Trophoblastic Disease IX. Rare Tumors 48. Rare Tumor: Melanoma—Lymphoma—Sarcoma

    Biography

    Pierluigi Benedetti Pani, John J. Kavanagh, Sergio Pecorelli, University of Brescia, Italy. Manuel Panalver, South Florida Gynecologic Oncology, Miami, USA.

    "…Everyone involved are the top minds on their subject….recommended for health science libraries, research libraries that support cancer programs, and cancer hospital/program libraries."
    -E-Streams

    "…focus[es] in on problems that may be of special complexity in the patient with a gynecologic cancer….a one-of-a-kind resource which every individual treating or caring for patients with gynecologic malignancies should have in their library."
    -Philip J. DiSaia, Professor, Department of Obstetrics and Gynecology; Director, Division of Gynecologic Oncology; and Chairman, Gynecologic Oncology Group, University of California, Irvine, U.S.A.