Pore-forming Peptides and Protein Toxins
Secretory Systems and Toxins
Toxins and Signal Transduction
Gianfranco Menestrina, M. Dalla Sera
January 30, 2003
Pore-forming proteins and peptides play a central role in bacterial pathogenesis, the immune response, defense from venomous attack, and innate immunity. These proteins attack and eliminate other organisms by punching an aqueous channel through their membranes, which disrupts appropriate cell...
Haya Lorberboum-Galski, Philip Lazarovici
May 30, 2002
Bacteria and plants produce powerful toxins that can cause a variety of diseases, some of which are lethal for many animal species. The mechanisms of action are common to many of these toxins and represent general pathways for the interaction of a number of biomolecules with target cells, such as...
Michal Linial, Alfonso Grasso, Phillip Lazarovici
October 20, 1998
This volume deals with the relationships between toxins and one of the most fundamental processes in any living cell - the secretory cycle. The reader will find up-to-date information on secretion, generated by experts in this fast evolving field. In the last decade extensive molecular and cellular...
Yehuda Gutman, Philip Lazarovici
May 22, 1997
Of the multitude of toxins known and the enormous variety of effects they cause, of particular interest are those that influence signal transduction. Intercellular communication by chemical signals is essential for the functioning of multicellular organisms. Many toxins exert their biological...