Cell-Penetrating Peptides: Processes and Applications

1st Edition

Ulo Langel

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CRC Press
Published May 29, 2002
Reference - 424 Pages
ISBN 9780429118326 - CAT# KE79665

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One of the major problems with drug delivery is the inability of large hydrophilic compounds to pass through the lipid membrane of the cell, thus making drugs such as polypeptides and oligonucleotides of limited therapeutic value. Until recently, the transport of such molecules into the cytoplasmic and nuclear compartments of living cells seemed a


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