Cell Culture Technology for Pharmaceutical and Cell-Based Therapies

1st Edition

Sadettin Ozturk, Wei-Shou Hu

CRC Press
Published August 30, 2005
Reference - 788 Pages - 23 Color & 102 B/W Illustrations
ISBN 9780824753344 - CAT# DK1481
Series: Biotechnology and Bioprocessing

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Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the importance of gene discovery and genomic technology development in the production of biotechnology products, tissue engineering, and cell-based therapies. Offering detailed guidance, they cover the steps leading up to the creation of viable therapies including host cell selection, cloning and gene amplification, bioreactor design and operation, protein purification, optimization, scale-up, and facility design.