1st Edition

Cancer Prevention and Management through Exercise and Weight Control

Edited By Anne McTiernan Copyright 2006
    606 Pages 57 B/W Illustrations
    by CRC Press

    606 Pages 57 B/W Illustrations
    by CRC Press

    “..it is increasingly clear that cancer is also a disease of inertia. In this book, a broadly multidisciplinary group presents the evidence and provides the recommendations. … The antidote to diseases of inertia is movement — let’s move!”

    John Potter, M.D.,Ph.D., from the Foreword

    The American Cancer Society estimates that a third of all cancer deaths could be prevented through avoidance of obesity and the rejection of sedentary lifestyles. The World Health Organization also supports this claim. Additionally, these and other organizations now recognize the role that activity can play in improving the quality of life for cancer patients.

    Cancer Prevention and Management through Exercise and Weight Control provides us with the support necessary to make a call to action. Itbrings together the contributions of world-class researchers to lay out the evidence and a plan of attack for coping with this crisis. The text begins by focusing on the research methods used in assessing the complex associations between activity, energy balance, and risk and prognosis. In comprehensive literature reviews, the authors consider the role of physical activity in the incidence of individual cancers, then explore the mechanisms that might explain this connection. They continue with a look at the relation between weight and cancer incidence, including a consideration of genetics.

    Research is also provided linking physical activity and weight control to a cancer patient’s quality of life and prognosis. The work concludes with ideas on how a plan of action might be implemented at the individual, clinical, and public health levels. It also provides guidance on incorporating exercise and diet recommendations into clinical oncology practice.

    Research Methods
    Observational Studies and Intervention Trials in Exercise, Diet, and Cancer
    Prevention Research: Ross L. Prentice
    Physical Activity Measurement: Barbara E. Ainsworth and Karen J. Coleman
    Measurement of Body Fat and Energy Balance: Melinda Irwin
    Physical Activity and Cancer Incidence
    Physical Activity and Cancer Incidence: Breast Cancer: Alpa V. Patel and Leslie Bernstein
    Physical Activity and Colorectal Cancer: Martha L. Slattery
    Physical Activity and Prostate Cancer Risk: Christine M. Friedenreich
    Mechanisms Associating Physical Activity with Cancer Incidence
    Physical Activity Effects on Sex Hormones: Anne McTiernan
    Exercise and Insulin Resistance: Laura Lewis Frank
    Exercise and Immune Function: Catherine M. Wetmore and Cornelia M. Ulrich
    Exercise and Prostaglandins: María Elena Martínez
    Mechanisms Associating Obesity with Cancer Incidence: Animal Models: Henry J. Thompson, Weiqin Jiang, and Zongjian Zhu
    Physical Activity Intervention Studies in Humans: Anne McTiernan
    Genetics, Physical Activity, and Cancer: Tuomo Rankinen
    Overweight/Obesity and Cancer Incidence
    Obesity, Weight Change, and Breast Cancer Incidence: Rachel Ballard–Barbash
    Body Size, Obesity, and Colorectal Cancer: Martha L. Slattery
    Endogenous Hormone Metabolism and Endometrial Cancer: Rudolf Kaaks and Annekatrin Lukanova
    Obesity and Pancreatic Cancer: Dominique S. Michaud and Edward Giovannucci
    Obesity and Overweight in Relation to Adenocarcinoma of the Esophagus: Cathrine Hoyo and Marilie D. Gammon
    Mechanisms Associating Obesity with Cancer Incidence
    Obesity and Sex Hormones: Rudolph Kaaks and Anne McTiernan
    Obesity and Insulin Resistance: George Blackburn and Belinda Waltman
    Obesity, Cytokines, and Other Inflammatory Markers: Elisa L. Priest and Timothy S. Church
    Mechanisms Associating Physical Activity with Cancer Incidence: Animal
    Models: Lisa H. Colbert
    Genetics, Obesity, and Cancer: Shelley Tworoger and Monica McGrath
    Physical Activity and Cancer Prognosis
    Quality of Life and Fatigue in Breast Cancer : Kerri Winters-Stone and Anna L. Schwartz
    Exercise and Quality of Life in Survivors of Cancer Other Than Breast: Kerry S. Courneya, Kristin L. Campbell, Kristina H. Karvinen, and Aliya B. Ladha
    Physical Activity and Physiological Effects Relevant to Prognosis: Page E. Abrahamson and Marilie D. Gammon
    Energy Balance and Cancer Prognosis
    Breast Cancer: Pamela J. Goodwin
    Colon, Prostate, and Other Cancers: Cheryl L. Rock
    Implementation   
    Physical Activity and Energy Balance: Mikael Fogelholm
    Diet and Other Means of Energy Balance Control: David Heber and Susan Bowerman
    Population-Based Approaches to Increasing Physical Activity: Fiona Bull
    Incorporating Exercise and Diet Recommendations into Primary Care Practice: Nicolaas P. Pronk
    Promoting Physical Activity in Cancer Survivors: Anna L. Schwartz and Kerri Winters-Stone
    Obesity and Early Stage Breast Cancer Outcome: Rowan T. Chlebowski and Michelle L. Geller
    Incorporating Weight Control into Management of Patients with Early
    Breast Cancer in the U.K.: Michelle Harvie and Anthony Howell
    Index

    Biography

    Anne McTiernan, M.D., Ph.D., is a faculty member in the Division of Public Health Sciences at the Fred Hutchinson Cancer Research Center in Seattle, Washington, and a research professor in the University of Washington Schools of Medicine and Public Health and Community Medicine.

    “… This volume is one of the only of its kind dedicated to helping healthcare providers establish a concrete plan allowing patients to control weight gain through exercise in order to forestall cancer. Expert researchers do an outstanding job delineating this material within a logical framework, looking at ways that physical activity impacts the incidence of cancer in the breast, prostate and colorectal regions … it promotes a step away from drug-based therapies in favor of a more holistic approach to mitigating cancer risks. Bluntly, it’s a message [to] those practicing medicine in the Western world should pay close and careful attention to. … Recommended to all primary care physicians (in addition to dieticians and nurse practitioners) who serve as a patient’s first-line of defense against disease. In addition, this volume is highly recommended to all Health Science libraries because of its well-detailed and erudite examination of the influence physical activity has on the processes of cancer.”
    — John Aiello, in The Electric Review


    “… is a collection of 35 chapters organized into 8 sections, each covering different aspects of the complex relationships among body weight, physical activity, cancer incidence, and cancer prognosis. … Each chapter provides a short review and summary of research studies that have addressed a variety of methodological, epidemiological, experimental, and clinical issues related to the prevention and management of different cancers through physical activity and body-weight management. … The organization of the chapters into section is logical, and each chapter includes a list of contents at the beginning. … would be of value to any clinicians who works with patients who have cancer and those who have survived it. It would be an especially helpful resource to anyone who wants to learn more about the current state of knowledge in the relatively new linkage of cancer management, obesity, genetics, and physical activity.”
    —Anthony E. Kincaid, Associate Professor, Department of Physical Therapy, Creighton University, Nebraska, in Physical Therapy, Vol. 87, No. 5, p. 615, May 2007


    “… The present volume is not a rehash of some long-past symposium. Rather, it contains 35 invited contributions, each with 50-200 references. … In all, this text provides a very thorough, evidence-based summary of current knowledge in a rapidly growing area of research, and it will be an important resource for those working on exercise, obesity and cancer.”
    —Roy J. Shephard in Canadian Journal of Applied Physiology, June 2007

    "The research presented in McTiernan’s text is truly ground-breaking… Bluntly, it’s a message those practicing medicine in the Western world should pay close and careful attention to… Recommended to all primary care physicians (in addition to dieticians and nurse practitioners) who serve as a patient’s first-line of defense against disease. In addition, this volume is highly recommended to all Health Science libraries because of its well-detailed and erudite examination of the influence physical activity has on the processes of cancer."

    --The Electric Review