1st Edition

Cancer Biomarkers

Edited By Alexandros G Georgakilas Copyright 2013
    382 Pages 8 Color & 15 B/W Illustrations
    by CRC Press

    This unique synthesis of chapters from top experts in their fields, targets the very important and upcoming area of cancer biomarkers and the need for better and more rigorous design and clinical trial. The book covers several aspects of cancer molecular markers from innovation, screening, controversies and future directions. The primary target audience for the book includes PhD and MD students, researchers, biologists, medical doctors and professionals who are interested in mechanistic studies on cancer diagnosis and translational benefits from personalized cancer treatment using the new era of biomarkers.

    Improving Research on Biomarkers for Early Detection and Screening of Cancers
    Claire S. Zhu, Paul F. Pinsky, and Christine D. Berg
    Biomarkers of Oxidative Stress in Carcinogenesis
    Humberto Rodriguez-Rocha, Aracely Garcia-Garcia, and Rodrigo Franco
    β-Catenin: a Novel Biomarker and Therapeutic Target in Liver Cancer
    Anupam Bishayee
    Urine Biomarkers for Prostate Cancer Detection
    Yan-Hua Chen, Art A. Rodriguez, and Qun Lu
    Ectodomain Shedding as a Mechanism to Generate Cancer Biomarkers (Ectomarkers)
    Maria J. Ruiz-Echevarria, Xiaofei Chen, and Ryan F. Overcash
    The BRCT Signaling ‘landscape’: Emerging Concepts and Implications in Tumorigenesis and Cancer Diagnostics
    Dimitris Mastellos and George Nounesis
    Cellular Senescence and Cancer Development: Antagonistic and Synergistic Relations
    Dimitris Kletsas
    Micro-RNAs: From Regulators of Gene Expression to Cancer Biomarkers
    Stamatina Giannouli, Panagiotis Maragozidis, Konstantinos I. Gourgoulianis, and Nikolaos A.A. Balatsos
    Targeting PARP-1 in Breast Cancer: The Paradigm of a DNA Repair-based Therapeutic Strategy
    Francisco Javier Oliver, Jara Majuelos-Melguizo, José Manuel Rodriguez-Vargas, Ariannys González-Flores, A. Peralta-Leal, Laura López, and María Isabel Rodríguez
    Statins in Prostate Cancer: Prevention and Treatment
    Khaled Aziz and Phuoc T. Tran
    Mechanistic Aspects of Oxidative Stress Involvement in Human Environmental and Occupational Carcinogenesis
    Dominique Ziech, Aglaia Pappa, and Mihalis I. Panayiotidis

    Biography

    Georgakilas, Alexandros G