Cancer Biomarkers: Minimal and Noninvasive Early Diagnosis and Prognosis

Debmalya Barh, Angelo Carpi, Mukesh Verma, Mehmet Gunduz

January 30, 2014 by CRC Press
Reference - 951 Pages - 128 B/W Illustrations
ISBN 9781466584280 - CAT# K19030

USD$262.95

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Features

  • Presents most recent data and all promising current and upcoming early diagnostic noninvasive molecular markers
  • Introduces, in each chapter, physicians or scientists that have leading roles in respective cancer biomarker discoveries
  • Provides a readily available resource for doctors, clinicians, health care industries to recommend or develop early diagnostic and at-risk tests for various cancers
  • Affords use to cancer researchers for developing next-generation biomarkers, targets, and targeted therapeutics for various cancers
  • Contains information on biomarker market economics, test providers, patent information, etc.

Summary

 

Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer markers that are under development or currently in use. It deals with a majority of commonly prevalent cancers and can help anyone working in the health-care industry to recommend or develop early diagnostics, at-risk tests, and prognostic biomarkers for various cancers.

It explores the practice of determining biomarkers by their characteristics and relative methodologies, and presents the most recent data as well as a number of current and upcoming early diagnostic noninvasive molecular markers for many common cancers. It also considers the sensitivity and specificity of markers, biomarker market, test providers, and patent information.

Approximately 30-35 Cancer Specific Noninvasive Molecular Diagnostic Markers in a Single Volume

The book details the general and technical aspects of noninvasive cancer markers. It covers imaging, cutting-edge molecular technologies for biomarker development, and noninvasive or minimally invasive sources of molecular markers, as well as quality control and ethical issues in cancer biomarker discovery. It also provides a detailed account of brain, head and neck, and oral cancer markers, and provides information on a number of gastrointestinal cancers, lung cancer, and mesothelioma markers.

Emphasizes the Importance of Volatile Markers in Early Cancer Diagnosis

  • Presents noninvasive early molecular markers in urological cancers
  • Describes gynecological and endocrine cancer markers
  • Details noninvasive markers of breast, ovarian, cervical, and thyroid cancers
  • Addresses hematological malignancies 
  • Contains information on noninvasive molecular markers in myelodysplastic syndromes, acute myeloid leukemia, Hodgkin’s lymphoma, and multiple myeloma
  • Provides comprehensive information on diagnostic and prognostic biomarkers in cutaneous melanoma

This text considers molecular technologies for biomarker development, noninvasive or minimally invasive sources of molecular markers, and quality control and ethical issues in cancer biomarker discovery.