The Biotechnology and Bioprocessing series offers in-depth presentations from respected experts and thought leaders in academia and industry. Titles explore recent developments and best practices that facilitate successful commercialization of Biotech Products. The series focus is on technologies, process development improvements, and new applications that would result in production of safe and efficacious drugs utilizing robust, efficient and economical processes.
Stem Cells and Revascularization Therapies
Process Synthesis for Fuel Ethanol Production
Biotransformations and Bioprocesses
Nuala Calnan, Martin J Lipa, Paige E. Kane, Jose C. Menezes
June 16, 2017
This book addresses the rapidly emerging field of Knowledge Management in the pharmaceutical, medical devices and medical diagnostics industries. In particular, it explores the role that Knowledge Management can play in ensuring the delivery of safe and effective products to patients. The book also...
Anurag S. Rathore, Gail Sofer
May 09, 2012
Process Validation in Manufacturing of Biopharmaceuticals, Third Edition delves into the key aspects and current practices of process validation. It includes discussion on the final version of the FDA 2011 Guidance for Industry on Process Validation Principles and Practices, commonly referred to as...
Hyunjoon Kong, Andrew J. Putnam, Lawrence B. Schook
December 13, 2011
In the last few decades, significant advancements in the biology and engineering of stem cells have enabled progress in their clinical application to revascularization therapies. Some strategies involve the mobilization of endogenous stem cell populations, and others employ cell transplantation....
Cenk Undey, Duncan Low, Jose C. Menezes, Mel Koch
December 07, 2011
As with all of pharmaceutical production, the regulatory environment for the production of therapeutics has been changing as a direct result of the US FDA-initiated Quality by Design (QbD) guidelines and corresponding activities of the International Committee for Harmonization (ICH). Given the...
C.A. Cardona, O.J. Sanchez, L.F. Gutierrez
December 03, 2009
Process engineering can potentially provide the means to develop economically viable and environmentally friendly technologies for the production of fuel ethanol. Focusing on a key tool of process engineering, Process Synthesis for Fuel Ethanol Production is a comprehensive guide to the design and...
Abhinav A. Shukla, Mark R. Etzel, Shishir Gadam
July 07, 2006
The biopharmaceutical industry has become an increasingly important player in the global economy, and the success of these products depends on the development and implementation of cost-effective, robust and scaleable production processes. Bioseparations-also called downstream processing- can be a...
Sadettin Ozturk, Wei-Shou Hu
August 30, 2005
Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the...
Mukesh Doble, Anil Kumar Kruthiventi, Vilas Ganjanan Gaikar
March 24, 2004
From the laboratory to full-scale commercial production, this reference provides a clear and in-depth analysis of bioreactor design and operation and encompasses critical aspects of the biocatalytic manufacturing process. It clarifies principles in reaction and biochemical engineering, synthetic...
Rajni Hatti-Kaul, Bo Mattiasson
February 05, 2003
This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors...
William K. Wang
April 03, 2001
This text details the relationship between membrane technology and bioprocesses, discussing applications. This second edition refines and optimizes key features of the first edition - and features new illustrative case studies. The book examines advantages and disadvantages of using standard and...
Sang Yup Lee, E. Terry Papoutsakis
September 29, 1999
This unique reference/text presents the basic theory and practical applications of metabolic engineering (ME). It offers systematic analysis of complex metabolic pathways and ways of employing recombinant DNA techniques to alter cell behavior, metabolic patterns, and product formation. Treating ME...
Juan A. Asenjo
November 17, 1994
Describes the state-of-the-art techniques and methods involved in the design, operation, preparation and containment of bioreactor systems, taking into account the interrelated effects of variables associated with both upstream and downstream stages of the design process. The importance of the...