Nanobiocatalysis has rapidly developed into a subarea of enzyme biotechnology. It combines the advances in nanotechnology that have generated nanoscale materials of different sizes, shapes, and physicochemical properties, and the excellent characteristics of biocatalysts into an innovative technology. This book provides an overview of the various relations between nanotechnology and biocatalysis. It discusses the fabrication and application of nanomaterials for the immobilization of enzymes used in the sustainable production of goods and chemicals. Nanosupports have several advantages compared with bulk solid materials because of their high surface area, which results in a significantly reduced mass transfer limitation and comparatively high enzyme loading. These characteristics are also of great use for applications in the fields of enzymatic biosensors, biofuel cells, bioelectronics, and photoelectrochemical analyte detection, where conductive nanomaterials improve the rate of electron transfer. The book also presents an overview of nanotoxicology and covers nanostructured enzyme catalysis in organic solvents and its potential application for biodiesel production, probing of enzymatic activity, and identification of enzyme functions of inorganic nanoparticles as enzyme mimics.
Fundamentals of Nanotechnology
Torben Kodanek, Sara Sánchez Paradinas, Franziska Lübkemann, Dirk Dorfs, and Nadja C. Bigall
Biocatalysis: An Introduction
Peter Grunwald
Environmentally Benign Nanomaterial Synthesis Mediated by Culture Broths
Lihong Liu, Fang Xie, Xiuxia Meng, Vishnu Parek, and Shaomin Liu
Rational Design of Enzyme-Polymer Biocatalysts
Omkar V. Zore, Rajeswari M. Kasi, and Challa V. Kumar
Biological Strategies in Nanobiocatalyst Assembly
Ian Dominic F. Tabañag, and Shen-Long Tsai
Graphene-Based Nanobiocatalytic System
Michaela Patilaa , George Orfanakisa , Angeliki C. Polydera, Ioannis V. Pavlidis, and Haralambos Stamatis
Immobilization of Biocatalysts onto Nanosupports: Advantages for Green Technologies
Alan S. Campbell, Andrew J. Maloney, Chenbo Dong, and Cerasela Z. Dinu
Enzyme Immobilization on Membrane and Its Application in Bioreactors
Peng-Cheng Chen, Xue-Yan Zhu, Jin Lia, and Xiao-Jun Huang
Potential Applications of Nanobiocatalysis for Industrial Biodiesel Production
Avinesh Byreddy and Munish Puri
Enzymogel Nanoparticles Chemistry for Highly Efficient Phase Boundary Biocatalysis
Ananiy Kohut, Scott W. Pryor, Andriy Voronov, and Sergiy Minko
Recent Advances in Nanostructured Enzyme Catalysis for Chemical Synthesis in Organic Solvents
Zheng Liu, Jun Ge, Diannan Lu, Guoqiang Jiang, and Jianzhong Wu
Probing Enzymatic Activity by Combining Luminescent Quantum Dots, Gold Nanoparticles and Energy Transfer
Naiqian Zhan, Goutam Palui, Wentao Wang, and Hedi Mattoussi
FRET Reporter Molecules for Identification of Enzyme Functions
Jing Mu, Hao Lun Cheong, and Bengang Xing
Quantum Dot Architectures on Electrodes for Photoelectrochemical Analyte Detection
Mark Riedel, Daniel Schäfer, and Fred Lisdat
Inorganic Nanoparticles as Enzyme Mimics
Ruben Ragg, Karsten Korschelt, Karoline Herget, Filipe Natalio, Muhammad Nawaz Tahir, and Wolfgang Tremel
Enzyme Nanocapsules for Glucose Sensing and Insulin Delivery
Wanyi Tai and Zhen Gu
Nanostructured Materials for Enzymatic Biofuel Cells
Takanori Tamaki
Enzymatic Biofuel Cells on Porous Nanostructures
Dan Wen and Alexander Eychmüller
Nanoplasmonic Biosensors
Bruno P. Crulhas, Caroline R. Basso, and Valber A. Pedrosa
Enzyme Biocomputing: Logic Gates and Logic Networks to Interface and Control Materials
Marcos Pita
Functional Nano-Bio Conjugates for Targeted Cellular Uptake and Specific Nanoparticle–Protein Interactions
Sanjay Mathur, Shaista Ilyas, Laura Wortmann, Jasleen Kaur, Isabel Gessner
Cell-Free Expression–Based Microarrays: Applications and Future Prospects
Apurva Atak and Sanjeeva Srivastava
Overview of the Current Knowledge and Challenges Associated With Human Exposure to Nanomaterials
Ali Kermanizadeh, Kim Jantzen, Astrid Skovmand, Ana C. D. Gouveia, Nicklas R. Jacobsen, Vicki Stone, and Martin J. D. Clift
Biography
Peter Grunwald studied chemistry at the University of Saarbrücken and the University of Hamburg, Germany, where he graduated in the field of high-frequency spectroscopy, and then became a staff member of the Institute of Physical Chemistry. After receiving his PhD in physical chemistry from the Department of Chemistry at the University of Hamburg, he founded a biotechnology research group. He was appointed professor in 2001. His research interests focus on the preparation and properties of immobilized enzymes, kinetics of enzymes in organic solvents, and interactions between biocatalysts and heavy metal ions. Prof. Grunwald is also interested in chemical education, including curriculum development.
