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AY's Neuroanatomy of C. elegans for Computation provides the neural circuitry database of the nematode Caenorhabditis elegans, both in printed form and in ASCII files on 5.25-inch diskettes (for use on IBM® and compatible personal computers, Macintosh® computers, and higher level machines). Tables of connections among neuron classes, synapses among individual neurons, gap junctions among neurons, worm cells and their embryonic origin, and synthetically derived neuromuscular connections are presented together with the references from which the data were compiled and edited. Sample data files and source codes of FORTRAN and BASIC programs are provided to illustrate the use of mathematical tools for any researcher or student interested in examining a natural neural network and discovering what makes it tick.
Table of Contents
CAENORHABDITIS ELEGANS IN COMPUTATIONAL RESEARCH. A BRIEF HISTORY. THE ORGANISM. A MODEL FOR STUDYING NERVOUS SYSTEMS BY COMPUTATION. Data Collection and Refinement. Data Translation and Manipulation. Computational Anatomy. COMPUTATIONS ON THE NERVOUS SYSTEM: SOME RESULTS. MOTIVATION, TOOLS, AND EARLY OBSERVATIONS. NUMERICAL CHARACTERIZATION. ANATOMICAL COMPUTATIONS. INHIBITION AND STABILITY. OTHER SPECULATION. SUGGESTIONS ON SIGNAL PROCESSING REPRESENTATION. REFRACTORY PERIOD AND THRESHOLD. DATA IN MACHINABLE FORM. README.1ST (GUIDELINES FOR THE C. ELEGANS DATABASE). Purpose. Media and . Directions. Nomenclature and Conventions. Distribution Agreement. NEURCLAS FILE SET (TABLE OF CONNECTIONS AMONG NEURON CLASSES). NEURCLAS.TXT. NEURCLAS. PRN. GAPJUNC FILE SET. (TABLE OF GAP JUNCTIONS AMONG NEURONS). GAPJUNC. TXT. GAPJUNC.PRN. LEGENDGO FILE SET (TABLE OF LEGENDS FOR THE PREPOSGO FILE SET). LEGENDGO.TXT. LEGENDO. PRN. PREPOSGO FILE SET (TABLE OF SYNAPSES AMONG NEURONS). PREPOSGO.TXT. PREPOSGO.PRN. PARTLIST FILE SET (TABLE OF ALL WORM PARTS (CELLS) AND CELL LINEAGES). PARTLIST.TXT. PARTLIS1.PRN. PARTLIS2.PRN. MOTORCON FILE SET (TABLE OF SYNTHETIC NEUROMOTOR CONNECTIONS). MOTORCON.TXT. MOTORCON.PRN. SAMPLE COMPUTER PROGRAMS. README.1ST. Purpose. Requirements. Direction. THE BASIC PROGRAMS. DISPLAY.BAS. MAKEDATA.BAS. ELEGRAPH.BAS. PLOT100.BAS. THE FORTRAN PROGRAMS. MAKELIST.FOR. CONNECT.FOR. EIGCRAY.FOR. BIBLIOGRAPHY AND ANNOTATIONS. BOOKS WE USED AND WHY. REFERENCES TO C. ELEGANS ANATOMY. MATHEMATICAL AND COMPUTATIONAL TOOLS. MATHEMATICAL MODELS. PERSPECTIVES.
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