Autologous Stem Cell Transplantation: Biological and Clinical Results in Malignancies

1st Edition

Angelo Carella

Routledge
Published November 21, 1997
Reference - 600 Pages
ISBN 9783718659333 - CAT# RU39936

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Summary

This textbook integrates basic research and clinical aspects underlying the most recent results in those malignant diseases where progress is most effective.
Recent evidence shows that higher doses are better in inducing higher cure rates in hematological neoplasias, although myeloblation related to dose intensity can be a limiting factor. The toxicity can now be controlled with autologous marrow and peripheral blood progenitor cell transplantation, used with or without growth factors. The combination of high dose chemoradiotherapy followed by re-infusion of autologous stem cells constitute a dramatic advance in the treatment of refactory and relapse hematological neoplasias.

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