Atlas of Time Lapse Embryology

Summary

Unlike conventional single daily observations, time lapse technology provides hundreds of images, which allows pinpointing of key events in the embryo’s in vitro development as well as the detection of brief but significant critical changes. This information is beneficial in selecting the most viable embryos from a cohort and increases the chances of a positive outcome.

The Atlas of Time Lapse Embryology describes in detail the technology and techniques surrounding time lapse embryology. The book also covers the clinical aspects of time lapse imaging, morphokinetic timings, implantation data, fertilization, compaction, blastulation, irregular cleavages, multinucleation, vacuolation, zona defects, and other topics.

The book is easy to read, practical, and illustrated with dozens of images and video clips to help explain a variety of concepts. It will help practitioners to better understand how time lapse monitoring may dramatically increase flexibility in the IVF clinic, and most importantly, enhance clinical outcomes.

Table of Contents

Equipment Required for Time Lapse Observations in In Vitro Fertilization
Louise Best

Clinical Aspects of Time Lapse Imaging
Alison Campbell

Time Lapse, the Cell Cycle, Distribution of Morphokinetic Timings, and Known Implantation Data
Alison Campbell

Gender and Morphokinetics Correlation
Samantha Duffy

Polar-Body Extrusion
Colleen Lynch and Mercedes Reguiera

Fertilization: Pronuclear Formation and Fading
Louise Kellam and Laina Murphy

Clinical Results: Dynamic Aspects—Fragmentation
Sue Montgomery

Number of Pronuclei and Ploidy in IVF /ICSI—Derived Embryos
Abigail A. Burchill

Dynamic Aspects: Compaction
Sue Montgomery

Blastulation
Sue Montgomery

Hatching of the Human Blastocyst
Louise Kellam

Irregular Cleavages
Kathryn Berrisford and Ellen Cater

Reverse Cleavage/Blastomere Fusion
Davina Hulme

Smooth Endoplasmic Reticulum Clusters
Cath Drezet

Multinucleation
Claire Shearer

Vacuolation
Rachel Smith

Granular Cytoplasm
Sarah Foley

Zona Defects
Gerri Emerson

The Patient Perspective
Samantha Duffy

Editor(s) Bio

Edited by

Alison Campbell, M. Med. Sci, head of embryology, CARE Fertility Group, Nottingham, UK

Simon Fishel, PhD, professor of human reproduction and CEO, CARE Fertility Group, Nottingham, UK