1st Edition
Assisted Reproductive Technologies Quality and Safety
Worldwide, approximately 500,000 in vitro fertilization cycles are performed every year. Although the best possible result is a healthy child, the technology carries a number of varying risks and complications leading to a trade-off between the efficacy of these treatments and their quality and safety. Drawing on contributions from international experts with academic and clinical backgrounds, Assisted Reproductive Technologies: Quality and Safety presents an analysis of the medical risks and complications involved in reproductive medicine.
Putting the intricacies of reproductive health in the spotlight, the book describes side-effects, risks, and complications related to ART treatments. It discusses ovarian hyperstimulation syndrome, demonstrates the impact of judicious elective single embryo transfer, and focuses heavily on multiple pregnancy as the major risk factor of ART. The editors highlight the relatively less likely, but important risks of oncogenic complications, bleeding at the time of ovum retrieval, and the even smaller but still existing risk for maternal mortality. They include discussions of non-medical factors that can have a major impact on people's lives such as psychological, sexual, financial, moral, ethical, and philosophical dilemmas.
In today's litigious climate, modern management of any clinic is all about minimizing risks and complications. Thoroughly addressing quality and safety issues in ART, this book provides succinct, up-to-date information on quality care in reproductive medicine.
Epidemiology of Multiple Pregnancy Including Natural versus Iatrogenic Multiple Pregnancy, A. Pinborg and A.N. Andersen
Obstetric Risks and Neonatal Complications of Twin Pregnancy and Higher-Order Multiple Pregnancy, U.-B. Wennerholm
Prevention of Multiple Pregnancies after Non-In Vitro Fertilization Treatment, B. Cohlen and P.A. van Dop
Patient Selection for Single-Embryo Transfer, A. Strandell
Embryo Selection for Elective Single-Embryo Transfer, E. Van Royen
Impact of Elective Single-Embryo Transfer on the Total and Multiple Pregnancy Rate, J. Gerris
Elective Single-Embryo Transfer in the First Cycle of In Vitro Fertilization/Intracytoplasmic Sperm Injection, D. De Neubourg
National Experience with Elective Single-Embryo Transfer
Introduction, J. Gerris
Finland, S. Vilska and A. Tiitinen
Belgium, P. De Sutter and M. Dhont
Sweden, C. Bergh
The Netherlands, D. Braat and J. Kremer
Laboratory-Related Risks in Assisted Reproductive Technologies, J.P.W. Vermeiden
Timing of Embryo Transfer as Relevant to Twin Prevention, P. De Sutter and J. Gerris
Epidemiology and Pathophysiology of Ovarian Hyperstimulation Syndrome, A. Delvigne
Clinical Management and Therapy of Ovarian Hyperstimulation Syndrome, P.A. van Dop
Ovarian Hyperstimulation Syndrome: Prevention in IVF and Non-IVF Treatment, J. Guibert and F. Olivennes
Health-Economic Considerations Regarding Single- versus Double-Embryo Transfer, P. De Sutter and J. Gerris
Oncogenic Risks Related to Assisted Reproductive Technologies, P.A. van Dop, H. Klip, and C. Burger
Genetic Considerations Regarding Azoospermic and Severely Oligozoospermic Men, S. Repping, J. de Vries, and F. van der Veen
Preimplantation Genetic Diagnosis: Risks and Complications, I. Liebaers, K. Sermon, and E. Van Assche
Preimplantation Aneuploidy Screening: Myths and Facts, J. Van der Elst
Congenital Anomalies after In Vitro Fertilization/Intracytoplasmic Sperm Injection, M. Bonduelle
Miscellaneous Risks and Complications, P. De Sutter
Psychological Complications of Assisted Reproductive Technologies, J. Boivin and J. Takefman
Philosophical and Ethical Considerations Regarding Assisted Reproductive Technologies, G. Pennings
Appendix
Index
Biography
Jan Gerris MD PhD is Professor of Obstetrics, Gynecology & Fertility, Middelheim Hospital, Antwerp, BelgiumFrançois Olivennes MD PhD is Professor of Reproductive Medicine, Hôpital Cochin, Paris, FrancePetra De Sutter MD PhD is Professor at the Centre for Reproductive Medicine, Ghent University Hospital, Ghent, Belgium
