Aromatic C(sp2)−H Dehydrogenative Coupling Reactions: Heterocycles Synthesis

1st Edition

Bagher Eftekhari-Sis

CRC Press
Published November 18, 2019
Reference - 310 Pages - 100 B/W Illustrations
ISBN 9780367347291 - CAT# 320166

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This comprehensive text covers the research and development trends in the growing field of aromatic C–H dehydrogenative coupling reactions, leading to different types of heterocycles. The author provides answers to how these coupling reactions occur, what kinds of heterocycles are synthesized, and what their advantages are. The palladium-, rhodium-, iridium-, copper-, cobalt-, ruthenium-, and ferric-catalyzed aromatic C(sp2)–H dehydrogenative cross-coupling reactions are described in detail. A useful reference source for researchers and graduates in the field of heterocyclic chemistry and transition-metal-catalyzed dehydrogenative coupling reactions.


  • Comprehensive volume on the synthesis of benzo-heterocycles via aromatic C(sp2)–H bond activation.
  • Heterocycles are of paramount importance to medicinal chemistry and drug discovery.
  • Provides a comprehensive literature survey on the construction of heterocycles.
  • Reaction procedures and mechanistic explanations are included, which will appeal to those in fine chemicals and pharmaceutical companies.


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