While considerable advances have been made in management of psoriasis in the last ten years, there is still no absolute cure, and no simple, safe, and invariably effective treatment. Therefore, the need for an up-to-date, authoritative, visually stunning, practical aid to diagnosis continues to be paramount for effective treatment of this disease.
Written by Lionel Fry, one of the world's most distinguished dermatologists, this completely revised second edition is a full update of the internationally acclaimed first edition of An Atlas of Psoriasis. Copiously illustrated in color, including new high quality visual imagery only recently available, the atlas highlights new treatment options such as light therapy and topical, systemic, and immunomodulatory drugs. Providing an authoritative review of psoriasis, the book is an essential reference for dermatologists, dermatopathologists, internists, and family physicians.
EPIDEMIOLOGY AND HISTOLOGY
PROGNOSIS
GENETICS
Family Studies
Census Studies
Twin Studies
Human Leukocyte Antigens
Chromosome Loci and Possible Genes
ETIOLOGY
Environmental Triggers
Physical Trauma
Infections
Stress
Drugs
Hypocalcemia
Alcohol
Climate
PATHOGENESIS
Immunopathology
Antigen-Presenting Cells
Cytokines
Nature of the Antigen
Streptococcal Exotoxins
Cellular Streptococcal Proteins
Evidence for M Protein Being the Antigen in Psoriasis
Evidence for Other Cell Wall and Membrane Peptides Being the Antigen in Psoriasis
Are the Effector T Cells in Psoriasis CD4 or CD8?
How Do the T Cells Enter the Skin?
The Innate Immune System
CLINICAL FEATURES
Age of Onset
Sex Predilection
Morphology
SITES AND CLINICAL PATTERNS
Plaque Psoriasis
Guttate Psoriasis
Chronic Plaque Combined with Guttate Psoriasis
Koebner Phenomenon
Erythrodermic Psoriasis
Pustular Psoriasis
Acral Psoriasis
Seborrheic Psoriasis
Childhood Psoriasis
Diaper 'Psoriasis'
Linear Psoriasis
Psoriasis at Specific Sites
DIFFERENTIAL DIAGNOSIS
Chronic Plaque Psoriasis
Guttate Psoriasis
Erythrodermic Psoriasis
Generalized Pustular Psoriasis
Localized Pustular Psoriasis
Acral Psoriasis
Seborrheic Psoriasis
Childhood Psoriasis
Scalp Psoriasis
Psoriasis of the Palms and Soles
Flexural Psoriasis
Nails
Linear Psoriasis
PSORIATIC ARTHROPATHY
Epidemiology
Genetics
Clinical Features in Peripheral Arthropathy
Spinal Arthritis
Relationship Between Skin Lesions and Arthropathy
Relationship Between Nail Involvement and Arthropathy
Extra-Articular Features
Treatment
Prognosis
TREATMENT
Topical Drugs
Oral therapy
Combined Treatments
Biologicals
Future Treatments
References
Index
Biography
Lionel Fry
"In this slim but focused book, Professor Lionel Fry has captured all we need to know about eczema. …replete with diagrams, helpful reminders in illustrative form, and plenty of pictures of the many expressions of eczema. The teachings of the renowned Professor Fry are delightfully presented in both word and illustration."
-From the Foreword by Charles N. Ellis, MD, University of Michigan
